Oral Controlled Release Formulation Design and Drug Delivery (eBook, PDF)

Theory to Practice
Redaktion: Wen, Hong; Park, Kinam

• Format: PDF

Produktbeschreibung

This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.

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Produktdetails

• Verlag: For Dummies
• Seitenzahl: 376
• Erscheinungstermin: 10. September 2010
• Englisch
• ISBN-13: 9780470640470
• Artikelnr.: 37298495

Autorenporträt

HONG WEN, PhD, is a Fellow and Project Leader in the Department of Pharmaceutical Development at Novartis, as well as a core member of the Novartis TRD S&T committee. He has contributed to dozens of INDs/IMPDs in addition to several approved NDAs. His expertise spans from discovery support and preformulation to late-phase development of solid dosage forms. He also specializes in bioavailability enhancement for water insoluble drugs, oral sustained release (SR) formulations, and combination products (FDC). He has written fifteen publications, six presentations, and eight patents in the drug delivery and controlled release fields. KINAM PARK, PhD, is a Professor in the Department of Pharmaceutics and Showalter Distinguished Professor of Biomedical Engineering at Purdue University. He is also the President of Akina, Inc., specializing in drug delivery. Dr. Park is Editor-in-Chief of the Journal of Controlled Release among other journal and advisory board appointments. The recipient of the Controlled Release Society Founders Award in 2004, Dr. Park has published nine books, more than a hundred chapters, and more than two hundred journal articles, and holds sixteen patents.

Inhaltsangabe

Preface.
Contributors.
1 Introduction and Overview of Oral Controlled Release Formulation Design (
Hong Wen and Kinam Park).
2 Evolution of Oral Controlled Release Dosage Forms (Ping I. Lee and
Jian-Xin Li).
3 Biopharmaceutic Consideration and Assessment for Oral Controlled Release
(CR) Formulations (Hua Zhang and Jean M. Surian).
4 Preformulation Consideration for Drugs in Oral CR Formulation (Manching
Sherry Ku).
5 Polymers in Oral Modified Release Systems (Jiasheng Tu, Yan Shen,
Ravichandran Mahalingam, Bhaskara Jasti, and Xiaoling Li).
6 Oral Extended Release Hydrophilic Matrices: Formulation and Design (
Xiaoguang Wen, Ali Nokhodchi, and Ali Rajabi-Siahboomi).
7 Coating Systems for Oral Controlled Release Formulations (Linda A. Felton
).
8 Fluid Bed Coating and Granulation for CR Delivery (Yue Teng and Zhihui
Qiu).
9 Controlled Release using Bilayer Osmotic Tablet Technology: Reducing
Theory to Practice (Sheri L Shamblin).
10 Fast Disintegrating Tablets (Seong Hoon Jeong, Jaehwi Lee, and Jong Soo
Woo).
11 Buccal Drug Delivery Systems (John D. Smart and Gemma Keegan).
12 Oral Targeted Drug Delivery Systems: Gastric Retention Devices (Hamid
Omidian and Kinam Park).
13 Oral Targeted Drug Delivery Systems: Enteric Coating (Wendy Dulin).
14 Orally Administered Drug Delivery Systems to the Colon (Mirela Nadler
Milabuer, Yossi Kam and Abraham Rubinstein).
15 Dissolution Testing: In Vitro Characterization of Oral Controlled
Release Dosage Forms (Michele Xuemei Guo).
16 Challenges and New Technologies of Oral Controlled Release (Xiaoming
Chen, Hong Wen and Kinam Park).
17 Oral Controlled Drug Delivery: Quality By Design (QbD) Approach to Drug
Development (Shailesh Singh, Thirunellai G. Venkateshwaran and Stephen P.
Simmons).
18 Oral Controlled Release-Based Products for Life Cycle Management (Nipun
Davar and Sangita Ghosh).
19 Generic Oral Controlled Release Product Development: Formulation and
Process Considerations (Salah U. Ahmed and Venkatesh Naini).
20 The Science and Regulatory Perspectives of Emerging Controlled Release
Dosage Forms (Rakhi B. Shah and Mansoor A. Khan).
Index.

Rezensionen

"This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues". (Yahoo! Finance US, 19 January 2011)