Osteoporosis in Older Persons (eBook, PDF)

Pathophysiology and Therapeutic Approach
Redaktion: Duque, Gustavo; Kiel, Douglas P.

• Format: PDF

Produktbeschreibung

Osteoporosis in Older Persons - Pathophysiology and Therapeutic Approach has the most up-to-date information about the pathophysiology and new therapeutic alternatives. Until recently most effort concerning osteoporosis research was directed mainly at the mechanisms of a type of osteoporosis known as post-menopausal osteoporosis. It was only just recently that a new syndrome, osteoporosis in older persons, was recognized as a new entity with its own pathophysiology and potential treatments. Highlights of this book include:- - Many illustrations showing the basic biological pathways involved in bone aging, as well as the potential links between aging and the changes in bone biology - Figures showing the potential therapeutic targets in bone to prevent and treat osteoporosis, complemented by a complete review on the current treatments - Descriptions of the epidemiology of osteoporotic fractures and their impact on health care costs - Coverage of fractures and their relationship with falls, including new invasive and non-invasive therapeutic approach for osteoporotic fractures - A complete review of future treatments is included explaining their biological basis as well as their potential indications Written by leading clinicians and practitioners in the field this book will be of use to those involved with aging bone research, geriatricians, gerontologists, and bone biologists, as well as offering medical trainees an understanding of the mechanisms of osteoporosis in the older person, with a practical approach to diagnosis and treatment in mind.

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Produktdetails

• Verlag: Springer London
• Seitenzahl: 186
• Erscheinungstermin: 13. Oktober 2009
• Englisch
• ISBN-13: 9781846286971
• Artikelnr.: 37343493

Autorenporträt

Gustavo Duque, McGill University, Montréal, QC, Canada / Douglas P. Kiel, Harvard Medical School, Boston, MA, USA

Inhaltsangabe

Biology of Bone.- Aging and Bone.- Calciotropic Hormones.- Sex Steroids and Aging Bone.- Animal Models for Senile Osteoporosis.- Senile Osteoporosis as a Geriatric Syndrome.- Genetics of Osteoporosis in Older Age.- Fracture Epidemiology Among Individuals 75+.- Falls as a Geriatric Syndrome: How to Prevent Them? How to Treat Them?.- Non-Pharmacological Treatments for Falls and Fractures.- Medical Treatment of Age-Related Osteoporosis: Present and Future.- Treatment of Osteoporosis in Long-Term Care.- Fracture Care in the Elderly.

Rezensionen

From the reviews:

"The authors of this multiauthored book bring together new information on the molecular biology of bone physiology in this examination of osteoporosis in older persons. ... The intended audience includes all health practitioners who treat older patients with osteoporosis. Research scientists in the area will find this book useful as well. ... This book's demonstration of the complex relationship of bone health to adipose tissue and several powerful hormones will stimulate new thinking in the area of osteoporosis." (David O. Staats, Doody's Review Service, August, 2008)

"This is a simply outstanding compilation that provides a clear and concise review of the effect age has on the skeleton at the molecular/genetic level, in animal models as well as humans. ... It provides clinicians with an overview of cellular mechanisms leading to bone loss and researchers with insight into the clinical consequences of age-related skeletal change in older adults. That such a text has not previously been written and become a reference standard among clinicians, geriatricians, and researchers ... ." (Neil Binkley, JAMA, Vol. 300 (11), September, 2008)

Aus den Rezensionen:

"... Ziel der Autoren ist es, die Leser mit neuesten Informationen über die Osteoporose des betagten Menschen zu versorgen. ... Das Buch zeichnet aus, dass klar und übersichtlich die Verbindung zwischen Altern und den dazugehörigen Veränderungen in der Knochenbiologie aufgezeichnet werden ... Zudem werden in ... Abbildungen die ... therapeutischen Ziele zur Prävention und zur Behandlung der senilen Osteoporose aufgezeigt ... lnsgesamt ein Buch, das sich an Geriater, Orthopäden und ... anderen medizinischen Berufsgruppen wendet, die sich mit der medikamentösen Osteoporose und Sturzprophylaxe des geriatrischen Patienten beschäftigen ..." -- Prof. Dr. Bernd Fromm, in: Orthopädie Mitteilungen, 2009, Issue 1, S. 117 f.