David T. Felson, Hans-Georg Schaible

Pain in Osteoarthritis (eBook, PDF)

• Format: PDF

Produktbeschreibung

An authoritative investigation of the sources and treatment of osteoarthritic joint pain Millions of people throughout the world suffer from osteoarthritis (OA)--a medical condition causing its sufferers excruciating pain that is often disabling. This is the first book to offer clinicians an in-depth understanding of the biological sources of osteoarthritic pain and how they can be treated. Here, a team of leading international authorities has contributed state-of-the-art information on: * The Neuroscience of Articular Pain--spinal and peripheral mechanisms of joint pain; experimental models for the study of osteoarthritic pain; inflammatory mediators and nociception in arthritis; phantoms in rheumatology; and more * Osteoarthritis and Pain--joint mechanisms and neuromuscular aspects of OA; bone pain and pressure in OA joints; structural correlates of OA pain; and more * Treatment of Osteoarthritic Pain--general approaches to treatment; treatments targeting pain receptors; treatments targeting biomechanical abnormalities; and treatments targeting inflammation Whether you're a medical professional, researcher, student, or a generalist or specialist focusing on pain or arthritis, this is your one-stop reference for understanding and treating joint pain in osteoarthritis.

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Produktdetails

• Verlag: John Wiley & Sons
• Seitenzahl: 320
• Erscheinungstermin: 10. August 2010
• Englisch
• ISBN-13: 9780470930557
• Artikelnr.: 37300664

Autorenporträt

David T. Felson, Clinical Epidemiology Unit, Boston University School of Medicine, Boston, Massachusetts, USA. Hans-Georg Schaible, Institute of Physiology, University Hospital of Jena, Jena, Germany.

Inhaltsangabe

Preface. Acknowledgments. Contributors. PART I: THE NEUROSCIENCE OF
ARTICULAR PAIN. 1. Spinal Mechanisms Contributing to Joint Pain (Hans-Georg
Schaible). 2. Activation of Sensory Neurons in the Arthritic Joint (Blair
D. Grubb). 3. Changes in the Neural Substrate of Nociception in a Rat
Derangement Model of Osteoarthritis (James L. Henry). 4. Inflammatory
Mediators and Nociception in Osteoarthritis (Bruce L. Kidd, Jason J.
McDougall, and Julia J. Inglis). 5. Phantoms in Rheumatology (Candida S.
McCabe, Richard C. Haigh, Nicholas G. Shenker, Jenny Lewis, and David R.
Blake). 6. Mechanisms That Generate and Maintain Bone Cancer Pain (Juan
Miguel Jimenez-Andrade, Monica Herrera, and Patrick W. Mantyh). 7.
Symmetry, T-Cells, and Neurogenic Arthritis (Nicholas G. Shenker, David R.
Blake, Candida S. McCabe, Richard C. Haigh, and Paul I. Mapp). PART II:
OSTEOARTHRITIS AND PAIN. 8. Joint Mechanics in Osteoarthritis (Walter
Herzog, Douglas Bourne, and Aliaa Rehan Youssef). 9. Neuromuscular Aspects
of Osteoarthritis (Kenneth D. Brandt). 10. Pressure-Driven Intravasation of
Osseous Fat in the Pathogenesis of Osteoarthritic Pain (Peer A. Simkin).
11. Structural Correlates of Osteoarthritis Pain: Lessons From Magnetic
Resonance Imaging (Philip G. Conaghan). 12. Evidence of Sensitization to
pain in Human Osteoarthritis (Gunnar Ordeberg). 13. Current Perspectives on
the Clinical Presentation of Joint Pain in Human Osteoarthritis (Paul
Creamer). PART III: TREATMENT OF OSTEOARTHRITIC PAIN. 14. General Approach
to treating Osteoarthritic Pain: Targeting Biomechanics Inflammation and
Nociception (David T. Felson). 15. Neurobiological Mechanisms of
Osteoarthritic Pain and Analgesic treatment (Tuhina Neogi and Joachim
Scholz). 16. Exercise, Taping, and Bracing as Treatments for Knee
Osteoarthritis Pain (Kim Louise Bennell, Michael Anthony Hunt, and Rana
Shane Hinman). 17. Treating Inflammation to Relieve Osteoarthritic Pain
(David T. Felson). Index.