Recent research in cell death mechanism has rekindled interest in PARP's [Poly (ADP-Ribose) Polymerase] intriguing role in necrosis and apoptosis. PARP as a Therapeutic Target covers the clinical aspects of PARP inhibitors, an up-and-coming class of therapeutic agents that counteracts the damage done by free radicals. International experts currently working on ways to apply it discuss its therapeutic potential in various forms of ischemia, diabetes, arthritis, inflammatory bowel disease, and septic shock. The book provides a comprehensive understanding of how PARP works for researchers attempting to better design inhibitors for therapeutic purposes.
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