The book begins by discussing a very important and yet poorly known aspect of cellular metabolism; namely, the compartmentalization of intracellular cations such as sodium, calcium, and magnesium. This is followed by separate chapters on fundamentals of membrane conformational changes in the erythrocyte model; the structure and function of peroxisomes and their role in disease processes; the use of invertebrate models for studies of pathological reactions; and reactions of lysosomes to cellular injury. Subsequent chapters deal with the pathology of skeletal muscle membranes; the shock lung syndrome; cellular mechanisms involved in jaundice and cholestasis; and pathology of the endothelium.
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