Ram I. Mahato, Ajit S. Narang, Virender Kumar

Pharmaceutical Dosage Forms and Drug Delivery (eBook, ePUB)

Revised and Expanded

• Format: ePub

Produktbeschreibung

Completely revised and updated, this fourth edition elucidates the principles of pharmaceutics, biopharmaceutics, dosage form design, and drug delivery - including emerging new biotechnology-based treatment modalities. The authors integrate aspects of physical pharmacy, chemistry, biology, and biopharmaceutics into drug delivery.

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Produktdetails

• Verlag: Taylor & Francis
• Erscheinungstermin: 22. November 2024
• Englisch
• ISBN-13: 9781040154885
• Artikelnr.: 72253424

Autorenporträt

Ram I. Mahato is Parke-Davis Endowed Professor and Chairman of the Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE. He was a professor at the University of Tennessee Health Science Center in Memphis, Research Assistant Professor at the University of Utah in Salt Lake City, Senior Scientist at GeneMedicine, Inc., The Woodlands, TX, and as a postdoctoral fellow at the University of Southern California in Los Angeles, Washington University in St. Louis, and Kyoto University, Japan. He received PhD in Drug Delivery from the University of Strathclyde and BSPS from China Pharmaceutical University. He has published 168 papers, 17 book chapters, holds 4 US patents, and has edited/written 12 books and 14 journal issues (Total Google Citations= 14,609 and h-Index =70). He was a Feature Editor of the Pharmaceutical Research (2006-2013) and Editorial Board Member of eight journals. He is a CRS and AAPS Fellow, Permanent Member of BTSS/NIH Study section, and ASGCT Scientific Advisor. He is applying sound principles in pharmaceutical sciences in the context of the latest advances in life and material sciences to solve challenging drug delivery problems in therapeutics.

Ajit S. Narang works as a Vice President at Oric Pharmaceuticals in South San Francisco, CA. His primary expertise is in oral drug delivery. He holds over 18 years of pharmaceutical industry experience in the development of oral dosage forms and drug delivery platforms. Previously he worked as a Principal Scientist at Genentech, Inc. and Bristol-Myers Squibb, Co. (BMS) in New Brunswick, NJ in the Drug Product Science & Technology Department. In addition to BMS, he has worked for Ranbaxy Research Labs (currently a subsidiary of Daiichi Sankyo, Japan) and Morton Grove Pharmaceuticals (currently, Wockhardt USA). He holds undergraduate Pharmacy degree from the University of Delhi, India and graduate degrees in Pharmaceutical Sciences from Banaras Hindu University, India and the University of Tennessee Health Science Center (UTHSC) in Memphis, TN. He currently serves the Excipient Focus Group chair-elect for the American Association of Pharmaceutical Scientists (AAPS), Adjunct Faculty for the UTHSC, and Associate Faculty for the University of Phoenix, AZ. His current research interests include innovations in dosage form development and drug delivery technologies that enable pharmaceutical development of challenging molecules to resolve stability, pharmacokinetic, and pharmacodynamic issues. He has more than 40 publications and three pending patent applications and has contributed to the development of several marketed drug products.

Virender Kumar is an assistant professor of Pharmaceutics in the College of Pharmacy and Pharmaceutical Sciences at the University of Toledo Medical Center. He worked as a Research Assistant Professor and as a postdoctoral at the University of Nebraska Medical Center, Omaha. He received his PhD in Drug Delivery also from the UNMC. He worked as a scientist in A&Z Pharmaceuticals, New York, NY. He received a master in industrial pharmacy from Saint Johns' University, NY. He also received M. Pharm, and B. Pharm from Guru Jambheshwar University, Hisar, Haryana, India. He has published 43 papers, 6 book chapters, holds 1 US patent, and has edited/written 1 book and two journal issues.

Inhaltsangabe

Section I. Introduction
1. Drug discovery
2. Drug Development
3. Pharmaceutical Considerations
4. Biopharmaceutical Considerations
5. Pharmacy Math and Statistics
Section II. Physicochemical Principles
6. Complexation and Protein Binding
7. Chemical Kinetics and Stability
8. Interfacial Phenomena
9. Colloidal Dispersion
10. Surfactants and Micelles
11. Pharmaceutical Polymers
12. Rheology
13. Radiopharmaceuticals
14. Drug Delivery Systems
15. Organ-specific drug delivery
Section III. Dosage Forms
16. Suspensions
17. Emulsions
18. Pharmaceutical Solutions
19. Powders and Granules
20. Tablets
21. Capsules
22. Parenteral Dosage Forms
23. Semisolid Dosage Forms
24. Inserts, Implants, and Devices
Section IV. Pharmaceutical Biotechnology
25. Protein- and Peptide-Based Dosage Forms
26. Antibody Therapeutics
27. Biotechnology-Based Dosage Forms
28. Genome editing technologies
29. Immunotherapy
30. Answers
31. Index