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Through the use of practical examples and solutions, this volume examines various statistical applications and research issues in the pharmaceutical industry, particularly in clinical trials and bioequivalence studies. It covers the in vitro-in vivo correlation, and how it can be used in the drug development process. It discusses adaptive designs in clinical research, advanced statistical designs, and one- and two-sided statistical tests. It also examines interim and sequential analysis for clinical trials and bioequivalence studies, discusses assumptions and applications of nonparametric methods, and expands on the concepts of multiple and logistic regression.
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