Pharmacokinetics and Pharmacodynamics of Novel Drug Delivery Systems: From Basic Concepts to Applications (eBook, PDF)

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Redaktion: Gharat, Sankalp A.; Khan, Tabassum; Momin, Munira M.

• Format: PDF

Produktbeschreibung

The book delves into the intricate realm of pharmacokinetics and pharmacodynamics as they apply to modern advancements in drug delivery systems. It offers a comprehensive exploration of novel drug delivery methods, with a particular focus on nanoparticles and nanocarriers. The absorption, distribution, metabolism, and excretion processes of nanoparticles are extensively examined. It also covers various evaluation models, spanning from preclinical to clinical, aimed at assessing the effectiveness and safety of nanoparticles in drug delivery.

It also covers the integration of Artificial Intelligence and Machine Learning in pharmacokinetics and pharmacodynamics, showcasing how these cutting-edge approaches can enhance our understanding of drug behavior and optimize therapeutic outcomes. It serves as a comprehensive guide, highlighting the fusion of traditional pharmacological concepts with contemporary drug delivery systems and innovative technologies, all in the pursuit of refining medical treatments and patient care and is a valuable resource for academicians, researchers, and pharmacologists.

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Produktdetails

• Verlag: Springer Nature Singapore
• Seitenzahl: 393
• Erscheinungstermin: 28. August 2024
• Englisch
• ISBN-13: 9789819978588
• Artikelnr.: 71500263

Autorenporträt

Prof. Sankalp Gharat is presently working as an Assistant Professor in Department of Pharmaceutics at SVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, India. He has earlier served as Assistant Professor in the Department of Pharmaceutics (2018-2019) at Humera Khan College of Pharmacy, Mumbai, India. Before joining academics, he was associated with Macleods Pharmaceuticals R&D centre, as a Research scientist in formulation and development of Topical (ANDA) conventional and novel products in the Dermatological Section for regulated market (US and EU Market). He has an experience of working from product development at R&D level to scaling up of the products, executing exhibit batches and commercial batches of topical products. Several topical dosage forms developed by his team have received approval in US and EU and have been commercialized. He has worked as a Research Associate fellow (2014-2016) in University of Mumbai sponsored research project on cancer management. His research interests include formulation development of novel drug delivery and targeted systems based on nanotechnology for drug delivery to cancer, rheumatoid arthritis, psoriasis and ophthalmic. In his area of research, he has several national and international papers published in peer reviewed journals in collaboration with Laurentian University, Bhabha Atomic Research Centre, Ajman University of United Arab Emirates. He has received research project grants worth about 1 million INR. He has been awarded with "Promising Young Faculty Award 2023" and "Best Research Proposal Writing Faculty 2023" by SVKM's Dr. BNCP. He has secured first place for two consecutive years at the prestigious 15th and 16th AVISHKAR Research Convention-University of Mumbai, in Medicine and Pharmacy Category (2020-21 and 2021-22). Prof. Sankalp is a recipient of "AICTE Scholarship for 2014-2016" and "Meyer Organic Academic Excellence Award 2016" by Meyer Organics Pvt. Ltd for his academic performance in bachelor's programme. He has delivered several research talks and interacted with students of various Pharmaceutical Institutions. He is actively involved in training students for conducting cell culture-based experiments for toxicity testing of formulations and phytochemicals. He is a member of professional societies like Association of Pharmaceutical Teachers of India (APTI) and Controlled Release society (CRS-Indian Chapter) Prof. Munira Momin is a Professor and Principal of SVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, India. She has earlier served as Professor in the Department of Pharmaceutics (2012-2015) at Oriental College of Pharmacy, Navi Mumbai, India, as Associate professor (2005-2011) at L J Institute of Pharmacy, Ahmedabad, India and as Assistant professor (2003-2005) at L M College of Pharmacy, Ahmedabad and S K Patel College of Pharmaceutical Education and Research, Mehsana, India. Her research interest is in Targeteddrug delivery and bioengineered polymeric nanoparticles with a specialization in brain-targeted nanosystems. She has been conferred with prestigious Nehru-Fulbright Academic excellence in Higher education seminar for the year 2019. She is a recipient of Top Most Influential Principal (Pharmacy category), year 2022 for her contribution in administration, research and bringing positive changes among students by setting up social sensitivity cell at her institute. She has received research grant projects worth about 2.6 crores from Industry and Government funding agencies. Dr. Momin is a recipient of ACG-Best research Paper Award of IDMA during the year 2020-21 and M L Khurana Memorial Best research paper award by IPA for the papers published during 2008-09. She also a F H Jani Gold Medal for securing first merit during B Pharm program. She has also published more than 80 scientific articles in the peer-reviewed international journal and authored or co-authored numerous books and book chapters. She has 05 Granted Indian patents to her credit. She is a member of many professional societies, i.e, Indian Pharmaceutical Association (IPA), Association of Pharmaceutical Teachers of India (APTI), Society for Pharmaceutical Dissolution Science (SPDS), Controlled Release society (CRS-Indian Chapter). She is a scientific chair of Disso-India, an annual conference arranged by SPDS. Dr. Tabassum Khan is Professor, Department of Pharmaceutical Chemistry and Quality Assurance at SVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, India. She is recipient of the prestigious Erasmus+ Teaching Mobility Fellowship, ERASMUS Foundation, European Union programme 2023; Shastri Indo-Canadian Institute, Shastri Mobility Programme fellowship award 2018; P. D. Sethi National Award for Best research paper on HPTLC, 2017 and the Indian Pharmaceutical Association- B. Pharm Merit ward, 1990. She is on the Reviewer Board for Science Fund of The Republic of Serbia, 2023 and 2021; National Science Centre Poland, 2022; New Frontier Seed Grant Program, Network for Canadian Oral Health Research, Nova Scotia, Canada, Nov 2019 and 2018; Shastri Indo Canadian Institute, MHRD, India under the Collaborative research category, October 2019 and Medical Research Council, UK under the South Africa (Newton)-UK Antibiotic Accelerator 2019 program, 2019. Her thrust areas of research include medicinal chemistry, natural product chemistry and nanotechnology based drug development. She has been awarded research grants to the tune of 245 lac INR from Central and State Government funding agencies. She has 2 Indian patents, 78 publications and 8 book chapters to her credit with a total impact factor of 142, h-index of 17 and i10-index of 26. She is a Reviewer for several national and international journals belonging to RSC, ACS, Elsevier, Springer, Bentham. She is life member of Indian Pharmaceutical Association and Society of Pharmaceutical Education and Research and member of International Federation of Pharmacists and American Association of Pharmaceutical Scientists.

Inhaltsangabe

Chapter 1_ Introduction to Pharmacokinetics and Pharmacodynamic studies of Novel Drug Delivery Systems.- Chapter 2_ Absorption, Distribution, Metabolism and Excretion of Nanoparticles.- Chapter 3_ Pharmacokinetic, Pharmacodynamic, Preclinical and Clinical models for evaluation of nanoparticles.- Chapter 4_ Pharmacokinetics of nanocarriers and novel drug delivery systems.- Chapter 5_ Clinical applications of Pharmacokinetic and Pharmacodynamic studies of nanoparticles.- Chapter 6_ Artificial Intelligence and Machine learning in Pharmacokinetics and Pharmacodynamic Studies.