Claudia Tanja Mierke

Physics of Cancer: Second edition, volume 1 (eBook, ePUB)

Interplay between tumor biology, inflammation and cell mechanics

• Format: ePub

Produktbeschreibung

In order to increase the healing opportunities of cancer, it is important to impair the dissemination and the spreading of cancer cells from the initial tumor and the formation of metastases in other organs or tissues of the human body. The underlying physical principles of these oncological processes are a major constituent of the research field highlighted in Physics of Cancer.

In this edition, the following themes are addressed:
- Introduction to tumor biology from a biophysical point of view
- The role of the mechanical properties of cancer cells in cellular invasion
- The impact of the tumor microenvironment on cellular invasion
- The impact of the mechanical and biochemical interaction of cancer cells with other cells in transendothelial migration

This completely revised second edition is improved linguistically with multiple increases of the number of figures and the inclusion of several novel chapters such as actin filaments during matrix invasion, microtubuli during migration and matrix invasion, nuclear deformability during migration and matrix invasion, and the active role of the tumor stroma in regulating cell invasion.

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Produktdetails

• Verlag: Institute of Physics Publishing
• Seitenzahl: 479
• Erscheinungstermin: 24. Oktober 2018
• Englisch
• ISBN-13: 9780750317535
• Artikelnr.: 56812430

Autorenporträt

Claudia Tanja Mierke has a background in biology and molecular oncology and is head of the biological physics division at the University of Leipzig where she regularly teaches molecular and cell biology, biophysics and soft matter physics to physicists. She is concerned with various research areas developing our understanding of the physical aspects of cancer.