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This comprehensive textbook is the key resource for postgraduate trainees or residents in haematology. Now in its seventh edition, the book continues to provide everything the reader needs for examination preparation or clinical practice. Postgraduate Haematology discusses up-to-date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style. It presents essential information for everyday use and teaching, as well more detailed scientific background for more in-depth reading,…mehr
This comprehensive textbook is the key resource for postgraduate trainees or residents in haematology. Now in its seventh edition, the book continues to provide everything the reader needs for examination preparation or clinical practice. Postgraduate Haematology discusses up-to-date knowledge of the pathogenesis, clinical and laboratory features, management and treatment of a wide range of blood and bone marrow disorders in a concise and user friendly style. It presents essential information for everyday use and teaching, as well more detailed scientific background for more in-depth reading, accompanied by thoughtful referencing. The clearly illustrated full-colour figures and charts demonstrate key facts, and are supplemented by numerous high quality photomicrographs of blood cells and tissues. Over 51 chapters from international authors, including the WHO Classification of Haematopoietic and Lymphoid Tissues, Postgraduate Haematology provides an expert review of malignant and non-malignant haematology. * New sections reflect advances in the specialty, e.g. knowledge gained from new generation sequencing, latest anticoagulant drugs, diagnostic laboratory tools, and treatment strategies * Superb four-color illustrations and photomicrographs of blood cells and tissues throughout * Includes algorithms to aid with decision-making for treatment * Companion website featuring figures and tables from the book Arm yourself with the textbook of choice for trainees and practitioners in haematology.
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Autorenporträt
A. Victor Hoffbrand, MA, DM, FRCP, FRCPath, FRCP (Edin), DSc, FMedSci, Emeritus Professor of Haematology at University College London, London, UK. Douglas R. Higgs, MD, FRCP, FRS, Professor of Molecular Haematology & Director, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, UK. David Keeling, Consultant in Haemophilia and Thrombosis, Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals, Oxford, UK. Atul B. Mehta MA, MD, FRCP, FRC Path, Consultant Haematologist & Clinical Director, RFH Lysosomal Storage Disorders Unit, Royal Free Hospital, London, UK.
Inhaltsangabe
Contributor list vii
Preface to the seventh edition x
Preface to the first edition xi
1 Stem cells and haemopoiesis 1 Emma de Pater, Elaine Dzierzak
2 Erythropoiesis 11 Douglas R Higgs, Noémi Roy, Deborah Hay
3 Iron metabolism iron deficiency and disorders of haem synthesis 21 Clara Camaschella, A Victor Hoffbrand, Chaim Hershko
4 Iron overload 40 Clara Camaschella, A Victor Hoffbrand, Maria Domenica Cappellini
5 Megaloblastic anaemia 53 A Victor Hoffbrand
6 Haemoglobin and the inherited disorders of globin synthesis 72 Swee Lay Thein, David Rees
7 Sickle cell disease 98 Anne Marsh, Elliott P Vichinsky
8 Hereditary disorders of the red cell membrane and disorders of red cell metabolism 114 Paola Bianchi, Narla Mohandas
9 Acquired haemolytic anaemias 138 Modupe O Elebute, Rachel Kesse-Adu
