Principles of Gender-Specific Medicine (eBook, ePUB)

Gender in the Genomic Era
Redaktion: Legato J M. D., (Hon C)

• Format: ePub

Produktbeschreibung

The announcement that we had decoded the human genome in 2000 ushered in a new and unique era in biomedical research and clinical medicine. This Third Edition of Principles of Gender-Specific Medicine focuses, as in the past two editions, on the essentials of sexual dimorphism in human physiology and pathophysiology, but emphasizes the latest information about molecular biology and genomic science in a variety of disciplines. Thus, this edition is a departure from the previous two; the editor solicited individual manuscripts from innovative scientists in a variety of fields rather than the traditional arrangement of sections devoted to the various subspecialties of medicine edited by section chiefs. Wherever it was available, these authors incorporated the latest information about the impact of the genome and the elements that modify its expression on human physiology and illness. All chapters progress translationally from basic science to the clinical applications of gender-specific therapy and suggest the most important topics for future investigation.

This book is essential reading for all biomedical investigators and medical educators involved in gender-specific medicine. It will also be useful for primary care practitioners who need information about the importance of sex and gender in the prevention, diagnosis and treatment of illness.

Winner of the 2018 PROSE Award in Clinical Medicine from the Association of American Publishers!

• Outlines sex-specific differences in normal human function and explains the impact of age, hormones, and environment on the incidence and outcome of illness
• Reflects the latest information about the molecular basis of the sexual dimorphism in human physiology and the experience of disease
• Reviews the implications of our ever-improving ability to describe the genetic basis of vulnerability to disease and our capacity to alter the genome itself
• Illustrates the importance of new NIH guidelines that urge the inclusion of sex as a variable in research protocols

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 792
• Erscheinungstermin: 15. Mai 2017
• Englisch
• ISBN-13: 9780128035429
• Artikelnr.: 48301254

Inhaltsangabe

1. Normal and variant sex development
2. Gender DiagnosesJack Drescher
3. Gender Identity in Disorders of Sex Development
4. Female sexual function: the role of animal models in assessing female
sexual dysfunction
5. Fertility Treatment and Preservation in Transgender Men and Women
6. Standards of Care for the Health of Transsexual, Transgender and
Gender-Nonconforming People: An Introduction
7. Sex-dependent and -independent Mechanisms in External Genitalia
Development
8. The Transsexual Adult
9. Sexual and gender minority individuals in health care: strategies to
include sexual orientation and gender identity in health professions
education
10. Sex Influences Exist at All Levels of Human Brain Function
11. Sex differences in the brain: Focus on developmental mechanisms
12. Sexual dimorphisms in the nervous system of the nematode Caenorhabditis
elegans
13. Oxytocin and Brain Plasticity
14. Emotion and Gender-specific neural processing in men and women
15. Behind the Mask: the experience of assessment, diagnosis and living
with autism for girls and young women
16. The significance of gender in perinatal medicine
17. Intrauterine Development of Sex Differences - Fetal Programming
18. Battle of the sexes: How the selection of spermatozoa in the female
reproductive tract manipulates the sex ratio of offspring
19. All Cells have a sex: Studies of sex chromosome function at the
cellular level
20. Sex-specific implications of exposure to an adverse intrauterine
environment
21. Immune response - Impact of biological sex and gender
22. Geoepidemiology and the Impact of Sex on Autoimmune Diseases
23. Gender and gene regulation in human immunity
24. Sex and gender specific aspects - from cells to cardiovascular disease
25. Estrogen: Impact on Cardiomyocytes and the Heart
26. The Sexually Dimorphic Characteristics of the Pathophysiology and
Treatment of Atrial Fibrillation
27. Gender Differences in Chronic Obstructive Pulmonary Disease- Current
Knowledge and Deficits
28. Cancer: Gender differences at the molecular level
29. An Updated Overview of the Gender-Specific Response to Infection
30. Gender Based Differences in Mortality in Indian Children Aged 5 to 14
years
31. Consideration of biological sex in translating regenerative stem cell
therapies
32. Adipose-derived Stem Cells in Regenerative Medicine
33. Sex, Gender and Pain
34. Sex and gender differences in trauma victims presenting for treatment
35. Women Do Worse Than Men - Gender-Specific Differences in Burn Patients
36. Exercise physiology in Men & Women
37. Musculoskeletal complaints in male and female instrumental musicians
38. Nutritional Genomics and Biological Sex
39. Microbiome: Impact of gender on function & characteristics of gut
microbiome
40. Sex and Gender Differences in Sleep Disorders: An Overview
41. Gender differences in bladder and kidney cancers
42. The complex challenge of blood pressure regulation: influences of sex
and aging on sympathetic mechanisms
43. Gender at the Interface of Renal Aging: Physiological and Pathological
Perspectives
44. Gender differences in mobility of elderly: Measurements and
interventions to improve mobility
45. Personalized Medicine in Space Flight, Part I: The Space Context and
Standard Clinical Approaches
46. Personalized Medicine in Space Flight, Part II: Personalized Precision
Medicine Approaches
47. Robots and Gender
48. Cyborgs: Understanding and Mutual Treatment
49. Personalized Medicine and Challenges in Research and Clinical
Implementation
50. Biological Sex Differences in Humans and their Importance in
Pharmaceutical Drug Discovery and Development