Principles of Psychiatric Genetics (eBook, PDF)

Redaktion: John I. Nurnberger, Jr

• Format: PDF

Produktbeschreibung

Disorders of behavior represent some of the most common and disabling diseases affecting humankind; however, despite their worldwide distribution, genetic influences on these illnesses are often overlooked by families and mental health professionals. Psychiatric genetics is a rapidly advancing field, elucidating the varied roles of specific genes and their interactions in brain development and dysregulation. Principles of Psychiatric Genetics includes 22 disorder-based chapters covering, amongst other conditions, schizophrenia, mood disorders, anxiety disorders, Alzheimer's disease, learning and developmental disorders, eating disorders and personality disorders. Supporting chapters focus on issues of genetic epidemiology, molecular and statistical methods, pharmacogenetics, epigenetics, gene expression studies, online genetic databases and ethical issues. Written by an international team of contributors, and fully updated with the latest results from genome-wide association studies, this comprehensive text is an indispensable reference for psychiatrists, neurologists, psychologists and anyone involved in psychiatric genetic studies.

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Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 13. September 2012
• Englisch
• ISBN-13: 9781139557924
• Artikelnr.: 38276236

Inhaltsangabe

Preface; 1. Contribution of genetic epidemiology to our understanding of
psychiatric disorders Kathleen Reis Merikangas and Anibal Cravchik; 2. A
basic overview of contemporary human genetic analysis strategies Ondrej
Libiger and Nicholas J. Schork; 3. In silico analysis strategies and
resources for psychiatric genetics research Ali Torkamani, Trygve Bakken
and Nicholas J. Schork; 4. Gene expression studies in psychiatric disorders
Alexander B. Niculescu; 5. Pharmacogenetics in psychiatry Falk W. Lohoff;
6. Functional validation of candidate genetic susceptibility factors for
major mental illnesses: from protein chemistry, cell biology, animal study,
to human brain imaging Akira Sawa, Wanli W. Smith, Saurav Seshadri, Akiko
Hayashi-Takagi, Hanna Jaaro-Peled and Atsushi Kamiya; 7. Epigenetic
mechanisms in drug addiction and depression William Renthal and Eric J.
Nestler; 8. Panic disorder Ardesheer Talati and Myrna M. Weissman; 9. The
genetics of phobic disorders and generalized anxiety disorder Raymond R.
Crowe; 10. Genetic contributions to obsessive-compulsive disorder (OCD) and
OCD-related disorders Dennis L. Murphy, Pablo R. Moya, Jens R. Wendland and
Kiara Timpano; 11. Post-traumatic stress disorder Michael J. Lyons, Tyler
Zink and Karestan C. Koenen; 12. Antisocial behavior: gene environment
interplay Laura A. Baker, Catherine Tuvblad, Serena Bedzjian and Adrian
Raine; 13. Learning disabilities Shelley D. Smith; 14. Autism and autism
spectrum disorders Daniel H. Geschwind and Maricela Alarcon; 15. Genetics
of major depression James B. Potash; 16. The genetics of anorexia and
bulimia nervosa Andrew W. Bergen, Jennifer Wessel and Walter H. Kaye; 17.
Genetics and common human obesity R. Arlen Price; 18. Alcoholism Howard J.
Edenberg; 19. Nicotine dependence Sarah Hartz and Laura Bierut; 20.
Genetics of stimulant dependence Joseph F. Cubells and Yi-Lang Tang; 21.
Genetics of personality disorders C. Robert Cloninger; 22. Ethical issues
in behavioral genetics Stephen H. Dinwiddie, Jinger Hoop and Elliot
Gershon; 23. Genetics of Tourette syndrome and related disorders Maria G.
Motlagh, Thomas V. Fernandez and James F. Leckman; 24. Endophenotypes
Bernice Porjesz; 25. Developmental disorders Craig A. Erickson, Khendra I.
Peay and Christopher J. McDougle; Index.