Prion Biology (eBook, PDF)

Research and Advances
Redaktion: Beringue, Vincent

• Format: PDF

Produktbeschreibung

This title includes a number of Open Access chapters.This book contains a selection of chapters aimed to provide a better understanding prion structure and biology. Together these chapters provide an overview of prion biology and underscore some of the challenges we face if we want to understand how this lively pathogen propagates and evolves in ma

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 282
• Erscheinungstermin: 8. April 2013
• Englisch
• ISBN-13: 9781466578166
• Artikelnr.: 40068486

Autorenporträt

Dr. Vincent Béringue is working in the prion field for almost twenty years. He has obtained his PhD in 1998 from the AgroParisTech Institute in Paris, in the laboratory of late Dr. Dominique Dormont. After a MRC-funded postdoctoral position in the laboratory of Prof. John Collinge and Dr. Simon Hawke at Imperial College School of Medicine in London, he joined Dr. Hubert Laude's laboratory at INRA (National Institute for Agricultural Research) in Jouy-en-Josas in 2001, as permanent staff scientist. He is now head of lab in the Molecular Virology Immunology Department at INRA. His primary research interests include the biochemistry, diversity and evolution of animal and human prions.

Inhaltsangabe

Cellular Prion Protein Protects from Inflammatory and Neuropathic Pain.
Brain Transcriptional Stability Upon Prion Protein-encoding Gene
Invalidation in Zygotic or Adult Mouse. Highly Efficient Protein Misfolding
Cyclic Amplification. The Role of Glycophosphatidylinositol Anchor in the
Amplification of the Scrapie Isoform of Prion Protein in vitro. The
Octarepeat Region of the Prion Protein Is Conformationally Altered in
PrP(Sc). Prion Protein Self-Peptides Modulate Prion Interactions and
Conversion. Prpsc Spreading Patterns in the Brain of Sheep Linked to
Different Prion Types. Experimental H-type Bovine Spongiform Encephalopathy
Characterized by Plaques and Glial- and Stellate-type Prion Protein
Deposits. A Novel Form of Human Disease with a Protease-Sensitive Prion
Protein and Heterozygosity Methionine/valine at Codon 129: Case Report.
Molecular Interactions Between Prions as Seeds and Recombinant Prion
Proteins as Substrates Resemble the Biological Interspecies Barrier in
vitro. Quantitative Phosphoproteomic Analysis of Prion-infected Neuronal
Cells.