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Inhaltsangabe
1. Chemistry and Production of Cyclodextrins.- 1.1. Cyclodextrin - A Paradigmatic Model.- 1.2. Cyclodextrin Research in Japan.- 1.3. Industrial Production of Cyclodextrins.- 1.4. Process Development for the Production of ?-Cyclodextrin.- 1.5.The Preparation and Some Properties of Glucosyl-Cyclodextrins.- 1.6. Separation of Cyclodextrins with Gelchromatography and HPLC.- 1.7. Rapid and Simple Spectrophotometric Method for Determination of Micro-Amounts of Cyclodextrins.- 2. Enzymology, Toxicology and Metabolism.- 2.1. Enzymology of the Cyclodextrins.- 2.2. A Photometric Test for the Cyclisation Activity of Cyclodextrin-Glycosyltransperases.- 2.3. Action of CGT on Beta Limit Dextrin of Amylopectin.- 2.4. Absorption and Metabolism of (?-Cyclodextrin by Rats.- 2.5. Toxicity Studies of Beta-Cyclodextrin.- 2.6. Absorption and Elimination of Cyclodextrin Derivatives by Rabbits and Rats.- 2.7. Renal Effects of Parenterally Administered Methylated Cyclodextrins on Rabbits.- 2.8. The Purification and Properties of Cyclodextrin Glycosyltransferase /CGT-ase/ of Bacillus Macerans (Abstract).- 2.9. A Rapid Method for Determination of CGT-ASE Activity (Abstract).- 2.10. Enzymatic Investigations with Cyclodextrins (Abstract).- 3. Cyclodextrin-Complexes.- 3.1. Structure Aspects of Cyclodextrin Inclusion Compounds.- 3.2. Structural Properties of Chemically Modified Cyclodextrins: The Crystal Structure of an Inclusion Complex Between Adamantanol and per-2,6-0-Methyl-?-Cyclodextrin.- 3.3. Application of a Stoichiometric Model of Cyclodextrin Complex Formation.- 3.4. The Complex Formation of Cyclodextrins and Related (1?4)-?-D-Glucans as Revealed by the Spin Labeling Techniques.- 3.5. A Simple Rule for Predicting Circular Dichroism Induced in Aromatic Guests by Cyclodextrin Hosts inInclusion Complexes.- 3.6. Transfer of Organic Molecules through Aqueous Layers Mediated by CD's and CD-Derivatives.- 3.7. Resolution of Chiral Sulfinyl Compounds Via ?-Cyclodextrin Inclusion Complexes.- 3.8. Interactions of ?-Cyclodextrin with Ionic Detergents.- 3.9. Thermofractography of Cyclodextrin-Complexes by Classical and Overpressured TLC Techniques.- 3.10. Thermoanalytical Investigations on Cyclodextrin Inclusion Compounds.- 3.11. Chiral Conformation of Bilirubin, Biliverdin and Benzil in Association with Cyclodextrin.- 3.12. Investigation of Cyclodextrin Complexes by X-Ray Powder Diffraction.- 3.13. Ternary Complexes of ?-Cyclodextrin and Benzoic Acid (Abstract).- 3.14. Polarographic Determination of Guest-Molecules in the Presence of ?-Cyclodextrin (Abstract).- 3.15. Hydrolysis of Phosphorochloridothionates in the Presence of ?-Cyclodextrin (Abstract).- 3.16. Molecular Dynamics of CD-Complexes in Solution: A 13C - N.M.R. Study.- 4. Cyclodextrin-Derivatives.- 4.1. The Chemistry of Cyclodextrin Derivatives.- 4.2. Cyclodextrin Derivatisation: Directed Reaction of Silylated Intermediates.- 4.3. Preparative Methods and NMR Analysis for Silylated Derivatives of Cyclodextrin.- 4.4. Cyclodextrin Polymers: Types and Specific Properties.- 4.5. Preliminary Studies on Tablet Disintegration by Sorption Calorimetry.- 4.6. Water-Soluble Cyclodextrin Polymers and Their Complexing Properties.- 4.7. Cyclodextrin Polymers as Specific Sorbents.- 4.8. Cyclodextrin-Crown Ether Combination (Abstract).- 5. Cyclodextrins in Pharmaceuticals.- 5.1. Cyclodextrin in Pharmaceutical Industry.- 5.2. A Forecast for Application of Cyclodextrins in the Pharma-Industry.- 5.3. Effects of Cyclodextrins on the Hemolysis Induced with Phenothiazine Neuroleptics.- 5.4. EnhancedBioavailability of Digitalis Glycoside by Cyclodextrin Complexation.- 5.5. Influencing Drug Absorption by ?-Cyclodextrin Complexation.- 5.6. Complex Equilibrium and Bioavailability.- 5.7. Menadione-?-Cyclodextrin Complex: Chemical Properties and Biological Effects.- 5.8. Stabilization of Camomile Oil with ?-Cyclodextrin.- 5.9. Pharmacological Effect of Lidocaine Dimethyl-?-Cyclodextrin Inclusion Complex.- 5.10. Investigations of Digitalis Glycosides and their Cyclodextrin Complexes (Abstract).- 5.11. Effect of Several Drugs and Their CD-Complexes on Heart-Rhythm of Blabera Craniifer (Abstract).- 5.12. Reduction of Indomethacin Side Effect with ?-Cyclodextrin in Gastro-Intestinal Tract (Abstract).- 5.13. Cyclodextrins and Congeners in Parenteral Applications.- 6. Application of Cyclodextrins in Foods Agriculture and Other Industries.- 6.1. Cyclodextrins in Foods, Cosmetics and Toiletries.- 6.2. Production and Application of ?-Cyclodextrin Complexes in the Food Industry.- 6.3. Stabilisation and Controlled Release of Perfume in Detergents.- 6.4. Separation of Phenylalanine and Tyrosine from Protein Hydrolysates.- 6.5. Effect of Cyclodextrin on Growth Processes and Productivity of Plants.- 6.6. Manifestation of Growth Control Effect of Cyclodextrin (CD) in Biosynthesis of DNA, RNA and Proteins in Germinating Barley.- 6.7. Biological Effects of the Cyclodextrin Complexes of 2-Chloroethylphosphonic Acid.- 6.8. Recovery of Solvent Vapours from Gaseous Phase by Cyclodextrin Solutions.- 6.9. Quality Control of the ?-Cyclodextrin Inclusion Complexes of Volatile Oils and Materials (Abstract).- Author Index.
1. Chemistry and Production of Cyclodextrins.- 1.1. Cyclodextrin - A Paradigmatic Model.- 1.2. Cyclodextrin Research in Japan.- 1.3. Industrial Production of Cyclodextrins.- 1.4. Process Development for the Production of ?-Cyclodextrin.- 1.5.The Preparation and Some Properties of Glucosyl-Cyclodextrins.- 1.6. Separation of Cyclodextrins with Gelchromatography and HPLC.- 1.7. Rapid and Simple Spectrophotometric Method for Determination of Micro-Amounts of Cyclodextrins.- 2. Enzymology, Toxicology and Metabolism.- 2.1. Enzymology of the Cyclodextrins.- 2.2. A Photometric Test for the Cyclisation Activity of Cyclodextrin-Glycosyltransperases.- 2.3. Action of CGT on Beta Limit Dextrin of Amylopectin.- 2.4. Absorption and Metabolism of (?-Cyclodextrin by Rats.- 2.5. Toxicity Studies of Beta-Cyclodextrin.- 2.6. Absorption and Elimination of Cyclodextrin Derivatives by Rabbits and Rats.- 2.7. Renal Effects of Parenterally Administered Methylated Cyclodextrins on Rabbits.- 2.8. The Purification and Properties of Cyclodextrin Glycosyltransferase /CGT-ase/ of Bacillus Macerans (Abstract).- 2.9. A Rapid Method for Determination of CGT-ASE Activity (Abstract).- 2.10. Enzymatic Investigations with Cyclodextrins (Abstract).- 3. Cyclodextrin-Complexes.- 3.1. Structure Aspects of Cyclodextrin Inclusion Compounds.- 3.2. Structural Properties of Chemically Modified Cyclodextrins: The Crystal Structure of an Inclusion Complex Between Adamantanol and per-2,6-0-Methyl-?-Cyclodextrin.- 3.3. Application of a Stoichiometric Model of Cyclodextrin Complex Formation.- 3.4. The Complex Formation of Cyclodextrins and Related (1?4)-?-D-Glucans as Revealed by the Spin Labeling Techniques.- 3.5. A Simple Rule for Predicting Circular Dichroism Induced in Aromatic Guests by Cyclodextrin Hosts inInclusion Complexes.- 3.6. Transfer of Organic Molecules through Aqueous Layers Mediated by CD's and CD-Derivatives.- 3.7. Resolution of Chiral Sulfinyl Compounds Via ?-Cyclodextrin Inclusion Complexes.- 3.8. Interactions of ?-Cyclodextrin with Ionic Detergents.- 3.9. Thermofractography of Cyclodextrin-Complexes by Classical and Overpressured TLC Techniques.- 3.10. Thermoanalytical Investigations on Cyclodextrin Inclusion Compounds.- 3.11. Chiral Conformation of Bilirubin, Biliverdin and Benzil in Association with Cyclodextrin.- 3.12. Investigation of Cyclodextrin Complexes by X-Ray Powder Diffraction.- 3.13. Ternary Complexes of ?-Cyclodextrin and Benzoic Acid (Abstract).- 3.14. Polarographic Determination of Guest-Molecules in the Presence of ?-Cyclodextrin (Abstract).- 3.15. Hydrolysis of Phosphorochloridothionates in the Presence of ?-Cyclodextrin (Abstract).- 3.16. Molecular Dynamics of CD-Complexes in Solution: A 13C - N.M.R. Study.- 4. Cyclodextrin-Derivatives.- 4.1. The Chemistry of Cyclodextrin Derivatives.- 4.2. Cyclodextrin Derivatisation: Directed Reaction of Silylated Intermediates.- 4.3. Preparative Methods and NMR Analysis for Silylated Derivatives of Cyclodextrin.- 4.4. Cyclodextrin Polymers: Types and Specific Properties.- 4.5. Preliminary Studies on Tablet Disintegration by Sorption Calorimetry.- 4.6. Water-Soluble Cyclodextrin Polymers and Their Complexing Properties.- 4.7. Cyclodextrin Polymers as Specific Sorbents.- 4.8. Cyclodextrin-Crown Ether Combination (Abstract).- 5. Cyclodextrins in Pharmaceuticals.- 5.1. Cyclodextrin in Pharmaceutical Industry.- 5.2. A Forecast for Application of Cyclodextrins in the Pharma-Industry.- 5.3. Effects of Cyclodextrins on the Hemolysis Induced with Phenothiazine Neuroleptics.- 5.4. EnhancedBioavailability of Digitalis Glycoside by Cyclodextrin Complexation.- 5.5. Influencing Drug Absorption by ?-Cyclodextrin Complexation.- 5.6. Complex Equilibrium and Bioavailability.- 5.7. Menadione-?-Cyclodextrin Complex: Chemical Properties and Biological Effects.- 5.8. Stabilization of Camomile Oil with ?-Cyclodextrin.- 5.9. Pharmacological Effect of Lidocaine Dimethyl-?-Cyclodextrin Inclusion Complex.- 5.10. Investigations of Digitalis Glycosides and their Cyclodextrin Complexes (Abstract).- 5.11. Effect of Several Drugs and Their CD-Complexes on Heart-Rhythm of Blabera Craniifer (Abstract).- 5.12. Reduction of Indomethacin Side Effect with ?-Cyclodextrin in Gastro-Intestinal Tract (Abstract).- 5.13. Cyclodextrins and Congeners in Parenteral Applications.- 6. Application of Cyclodextrins in Foods Agriculture and Other Industries.- 6.1. Cyclodextrins in Foods, Cosmetics and Toiletries.- 6.2. Production and Application of ?-Cyclodextrin Complexes in the Food Industry.- 6.3. Stabilisation and Controlled Release of Perfume in Detergents.- 6.4. Separation of Phenylalanine and Tyrosine from Protein Hydrolysates.- 6.5. Effect of Cyclodextrin on Growth Processes and Productivity of Plants.- 6.6. Manifestation of Growth Control Effect of Cyclodextrin (CD) in Biosynthesis of DNA, RNA and Proteins in Germinating Barley.- 6.7. Biological Effects of the Cyclodextrin Complexes of 2-Chloroethylphosphonic Acid.- 6.8. Recovery of Solvent Vapours from Gaseous Phase by Cyclodextrin Solutions.- 6.9. Quality Control of the ?-Cyclodextrin Inclusion Complexes of Volatile Oils and Materials (Abstract).- Author Index.
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