Proinflammatory and Antiinflammatory Peptides (eBook, ePUB)

Redaktion: Said, Sami I.

• Format: ePub

Produktbeschreibung

"Analyzes the role of peptides in promoting or suppressing inflammation. Thoroughly examines the therapeutic potential of key peptides, analogs, agonists, and antagonists that influence cell injury and repair."

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 760
• Erscheinungstermin: 25. November 2020
• Englisch
• ISBN-13: 9781000145991
• Artikelnr.: 60475823

Autorenporträt

Sami I. Said

Inhaltsangabe

Part 1 Cell injury and inflammation: inflammation, cell injury and
apoptosis; proinflammatory and antiinflammatory response cytokines in the
inflammatory response. Part 1 Proinflammatory peptides: proinflammatory
peptides in sensory nerves of the airways; sensory neuropeptides and
bronchial hyperresponsiveness; the tachykinin family of peptides and their
receptors; endothelins in inflammation; endothelins in the lung;
proinflammatory peptides in relation to other inflammatory mediators;
cellular regulation of kinin receptors - potential roles in inflammation.
Part 3 Antiinflammatory peptides: modulation of inflammatory effects of
cytokines by the neuropeptide -MSH; regulation of VIP gene expression;
neuroregulation of pulmonary immune responses by VIP and substance P; role
of vasoactive intestinal peptide in myocardial ischaemia - reperfusion
injury; antiinflammatory actions of VIP in the lungs and airways; VIP
regulation of neuronal proliferation and differentiation; implications for
neuronal repair; neurotrophic action of VIP - from CNS ontogeny to
therapeutic strategy. Part 4 Modulation of peptide action - therapeutic
applications: long-acting VIP analogs; catalytic anti-VIP antibodies and
their relevance to the airways; enzymatic degradation of bradykinin;
enzymatic modulation of the tachykinins and VIP in the lung; therapeutic
effects and immunomodulatory activities of natriuretic peptides.