Protein Complexes that Modify Chromatin (eBook, PDF)

Redaktion: Workman, Jerry L.

• Format: PDF

Produktbeschreibung

Chromatin dynamics is a consequence of protein complexes that modify histones, remove histone modifications, mobilize nucleosomes or stabilize nucleosomes. A wide variety of such complexes have now been described. Some are abundant and may play global roles, others are more rare and specialized for functions at discreet loci. Several complexes share biochemical activities and genetic studies suggest overlapping functions. Many components of these complexes were first revealed in genetic screens, while others were discovered by novel biochemical approaches. This volume of Current Topics in Microbiology and Immunology reviews a wide variety of protein complexes that modify chromatin.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Springer Berlin Heidelberg
• Seitenzahl: 298
• Erscheinungstermin: 6. Dezember 2012
• Englisch
• ISBN-13: 9783642557477
• Artikelnr.: 53383175

Inhaltsangabe

Nucleosome Assembly and Remodeling.- Chromatin Proteins Are Determinants of Centromere Function.- HPI Complexes and Heterochromatin Assembly.- SMC Protein Complexes and the Maintenance of Chromosome Integrity.- Selective Gene Regulation by SWI/SNF-Related Chromatin Remodeling Factors.- The SWI/SNF Family of ATP-Dependent Chromatin Remodelers: Similar Mechanisms for Diverse Functions.- Changing the DNA Landscape: Putting a SPN on Chromatin.- The MYST Family of Histone Acetyltransferases.- N-CoR-HDAC Corepressor Complexes: Roles in Transcriptional Regulation by Nuclear Hormone Receptors.- The NuRD Complex: Linking Histone Modification to Nucleosome Remodeling.

Rezensionen

From the reviews: "This volume of Current Topics in Microbiology and Immunology entitled 'Protein Complexes that Modify Chromatin' takes the reader on a detailed voyage through chromatin. ... The book is divided into ten chapters, each contributed by experts in the field of chromatin. ... presents a detailed overview of the protein complexes that associates with chromatin. ... is a great reference for researchers who are specifically interested in chromatin and its associated proteins."(Yassmine Akkari, The Journal of the Association of Genetic Technologists, Vol. 30 (1), 2004) "This book provides timely reviews of several protein complexes that regulate gene expression and chromatin dynamics. Examples of such complexes include nucleosome assembly complexes, ATP-dependent chromatin remodeling complexes ... . These chapters will bring experts in the field up to date on several aspects of chromosome biology and will provide an exciting introduction to the field for new chromatin researchers." (Journal of Investigational Allergology & Clinical Immunology, Vol. 13 (3), 2003)