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Seminar paper from the year 2009 in the subject Health - Public Health, grade: 1,0, Johannes Gutenberg University Mainz (Institut für Medizinische Biometrie, Epidemiologie und Informatik), course: Epidemiology of infectious diseases, language: English, abstract: Since the advent of highly active antiretroviral therapy (HAART) in the mid 90s, the face of the HIV epidemic has changed considerably. Obvious progress has been made with respect to morbidity and mortality. But in spite of the effective medical treatment, quality of life (QOL) is still challenged by one of the most stigmatised diseases in the world. The aim of this review was therefore to sum up the up-to-date knowledge concerning QOL and to identify factors promoting QOL in HIV+ individuals. Another aim was to detect obvious gaps in knowledge that should be filled by further research activity.