Eudenilson L. Albuquerque

Quantum Chemistry Methods for Oncological Drugs (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Quantum Chemistry Methods for Oncological Drugs provides a comprehensive reference text for student, researchers, and academic staff across disciplines working in the field of Nanobiotechnology, who need to grasp the unique inter-relationship of the physical, chemical, and biological properties of oncological drugs and their interactions. It provides a theoretical/computational framework based on quantum chemistry and addresses key questions in which detailed analysis and precise predictions are always required.

The sophisticated molecular recognition of various natural biological materials has been used in the formation of a complex network of structures potentially useful for a variety of pharmaceutical applications. They offer solutions to many of the obstacles that need to be overcome, with accuracy not feasible with the technologies usually available in materials science. Important common challenges presented in this book are aspects related to the biology of cancer using our immunological checking points, specialized proteins that act as brakes in the immune system, allowing it to recognize and attack more efficiently only the cancer cells, avoiding the destruction of healthy cells as in conventional chemotherapy and radiotherapy treatments.

This book is devoted to this burgeoning area of Nanobiotechnology for oncological drugs and will be valuable in covering the new developments that have occurred in the last decade or so. It is aimed at graduate students, faculty members and other researchers in physics, chemistry, biology, pharmacology, and medicine.

• Comprehensive and up-to-date account of the main physical, chemical, biological, and pharmaceutical properties of oncological drugs and their interactions, using a theoretical/computational framework based on quantum chemistry
• Focuses on an exciting and dynamic area of research, not only in the academic world but also in the Nanobiotechnology industry
• Strong multidisciplinary content: the immediate future of pure and applied scientific research undoubtedly points to the interconnection and complementarity between different areas

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 256
• Erscheinungstermin: 29. Februar 2024
• Englisch
• ISBN-13: 9780443155314
• Artikelnr.: 70085177

Autorenporträt

Eudenilson L. Albuquerque is Professor of Physics and Biophysics, at the Department of Biophysics, UFRN, Brazil, where he served as Dean for Research and Graduate Studies (1987-1991). He has previously co-authored the books Polariton in Periodic and Quasiperiodic Structures (Elsevier, 2004) and Quantum Chemistry Simulation of Biological Molecules (Cambridge University Press, 2021).

Inhaltsangabe

PART I: QUANTUM CHEMISTRY: A REVIEW 1. From classical to quantum physics
(draft ready) 2. Main theoretical results 3. Computational approach
PART II: IMMUNE-ONCOLOGICAL DRUGS 4. Cancer Immunotherapy 5.
Immune-oncological drug Atezolizumab 6. Immune-oncological drug Nivolumab
7. Immune-oncological drug Pembrolizumab 8. Immune-oncological drug
Ipilimumab 9. Optoelectronics properties
PART III: TRANSVERSE ONCOLOGICAL DRUGS 10. Introduction 11. Oncological
drugs complexed with the Human Serum Albumin (draft ready) 12. Anti- Breast
cancer oncological drugs 13. Anti-Prostate cancer oncological drugs
PART IV: LOOKING AHEAD 14. The future of the oncological drugs