Recent Advances in iPSC Disease Modeling (eBook, ePUB)

Redaktion: Birbrair, Alexander

• Format: ePub

Produktbeschreibung

Recent Advances in iPSC Disease Modeling, Volume One addresses how induced pluripotent stem cells can be used to model various diseases. This new volume teaches readers about current advances in the field, describing the use of induced pluripotent stem cells to model several diseases in vitro, and thus enabling us to study the cellular and molecular mechanisms involved in different pathologies. Further insights into these mechanisms will have important implications for our understanding of disease appearance, development and progression. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation specialists.

In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cell types, tissues and organs using state-of-art techniques. Hence, these advantages have facilitated the identification of key targets and further defining on the molecular basis of several disorders.

• Provides an overview on the fast-moving field of induced pluripotent stem cell technology, regenerative medicine and therapeutics
• Covers the following diseases: severe congenital neutropenia, sickle cell and Diamond-Blackfan anemias, muscular dystrophies, Bernard-Soulier syndrome, familial hypercholesterolemia type II A, Werner syndrome, lysosomal storage diseases, and more
• Contains descriptions of cutting-edge research on the development of disease-specific human pluripotent stem cells

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 320
• Erscheinungstermin: 16. Juli 2020
• Englisch
• ISBN-13: 9780128232699
• Artikelnr.: 61689777

Inhaltsangabe

1. iPSCs for Modeling Lysosomal Storage Diseases 2. Sickle Cell Anemia: HBB
Haplotypes; Clinical Heterogeneity; iPSC Modelling 3. iPSCs for Modeling
mtDNA Diseases 4. iPSCs for Modeling Diamond Blackfan Anemia 5. Modeling
Severe Congenital Neutropenia in Induced Pluripotent Stem Cells 6. iPSCs
for Modeling Duchenne Muscular Dystrophy 7. Induced Pluripotent Stem Cell
Modelling of Genetic Small Vessel Disease 8. The Contribution of Human
Pluripotent Stem Cells to the Study of Myotonic Dystrophy Type 1 9. Induced
Pluripotent Stem Cells (iPSCs) for Modeling of Bernard-Soulier Syndrome 10.
iPSCs for Modelling Familial Hypercholesterolemia Type II A 11. iPSCs for
Modeling Elastin-Associated Vasculopathy 12. iPSCs for Modeling of
Sarcomeric Cardiomyopathies 13. Werner Syndrome iPS Cell, A Study of
Pathologic Aging