Sie sind bereits eingeloggt. Klicken Sie auf 2. tolino select Abo, um fortzufahren.
Bitte loggen Sie sich zunächst in Ihr Kundenkonto ein oder registrieren Sie sich bei bücher.de, um das eBook-Abo tolino select nutzen zu können.
Plant polyphenols are secondary metabolites that constitute one of the most common and widespread groups of natural products. They express a large and diverse panel of biological activities including beneficial effects on both plants and humans. Many polyphenols, from their structurally simplest representatives to their oligo/polymeric versions (also referred to as vegetable tannins), are notably known as phytoestrogens, plant pigments, potent antioxidants, and protein interacting agents.Sponsored by the scholarly society Groupe Polyph nols, this publication, which is the fifth volume in this…mehr
Plant polyphenols are secondary metabolites that constitute one of the most common and widespread groups of natural products. They express a large and diverse panel of biological activities including beneficial effects on both plants and humans. Many polyphenols, from their structurally simplest representatives to their oligo/polymeric versions (also referred to as vegetable tannins), are notably known as phytoestrogens, plant pigments, potent antioxidants, and protein interacting agents.Sponsored by the scholarly society Groupe Polyph nols, this publication, which is the fifth volume in this highly regarded Recent Advances in Polyphenol Research series, is edited by Kumi Yoshida, V ronique Cheynier and St phane Quideau. They have once again, like their predecessors, put together an impressive collection of cutting-edge chapters written by expert scientists, internationally respected in their respective field of polyphenol sciences. This Volume 5 highlights some of the latest information and opinion on the following major research topics about polyphenols: Chemistry, physicochemistry & materials science Biosynthesis, genetic & metabolic engineering Plant & ecosystem, lignocellulosic biomass Food, nutrition & health Natural medicine & Kampo Tannins & their functionsChemists, biochemists, plant scientists, pharmacognosists and pharmacologists, biologists, ecologists, food scientists and nutritionists will all find this book an invaluable resource. Libraries in all universities and research institutions where these disciplines are studied and taught should have copies on their bookshelves.
Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.
Die Herstellerinformationen sind derzeit nicht verfügbar.
Autorenporträt
Kumi Yoshida and Veronique Cheynier are the authors of Recent Advances in Polyphenol Research, Volume 5, published by Wiley.
Inhaltsangabe
Contributors xv Preface xix 1 The Physical Chemistry of Polyphenols: Insights into the Activity of Polyphenols in Humans at the Molecular Level 1 Olivier Dangles, Claire Dufour, Claire Tonnelé and Patrick Trouillas 1.1 Introduction 1 1.2 Molecular complexation of polyphenols 4 1.3 Polyphenols as electron donors 11 1.4 Polyphenols as ligands for metal ions 21 1.5 Conclusions 27 References 28 2 Polyphenols in Bryophytes: Structures, Biological Activities, and Bio- and Total Syntheses 36 Yoshinori Asakawa 2.1 Introduction 36 2.1 Distribution of cyclic and acyclic bis-bibenzyls in Marchantiophyta (liverworts) 37 2.3 Biosynthesis of bis-bibenzyls 39 2.4 The structures of bis-bibenzyls and their total synthesis 50 2.5 Biological activity of bis-bibenzyls 58 2.6 Conclusions 60 Acknowledgments 61 References 61 3 Oxidation Mechanism of Polyphenols and Chemistry of Black Tea 67 Yosuke Matsuo and Takashi Tanaka 3.1 Introduction 67 3.2 Catechin oxidation and production of theaflavins 71 3.3 Theasinensins 73 3.4 Coupled oxidation mechanism 75 3.5 Bicyclo[3.2.1]octane intermediates 77 3.6 Structures of catechin oxidation products 78 3.7 Oligomeric oxidation products 82 3.8 Conclusions 84 Acknowledgments 85 References 85 4 A Proteomic-Based Quantitative Analysis of the Relationship Between Monolignol Biosynthetic Protein Abundance and Lignin Content Using Transgenic Populus trichocarpa 89 Jack P. Wang, Sermsawat Tunlaya-Anukit, Rui Shi, Ting-Feng Yeh, Ling Chuang, Fikret Isik, Chenmin Yang, Jie Liu, Quanzi Li, Philip L. Loziuk, Punith P. Naik, David C. Muddiman, Joel J. Ducoste, Cranos M. Williams, Ronald R. Sederoff and Vincent L. Chiang 4.1 Introduction 90 4.2 Results 94 4.3 Discussion 101 4.4 Materials and methods 102 References 104 5 Monolignol Biosynthesis and Regulation in Grasses 108 Peng Xu and Laigeng Li 5.1 Introduction 108 5.2 Unique cell walls in grasses 109 5.3 Lignin deposition in grasses 110 5.4 Monolignol biosynthesis in grasses 111 5.5 Regulation of monolignol biosynthesis in grasses 114 5.6 Remarks 119 Acknowledgments 119 References 120 6 Creation of Flower Color Mutants Using Ion Beams and a Comprehensive Analysis of Anthocyanin Composition and Genetic Background 127 Yoshihiro Hase 6.1 Introduction 127 6.2 Induction of flower color mutants by ion beams 129 6.3 Mutagenic effects and the molecular nature of the mutations 131 6.4 Comprehensive analyses of flower color, pigments, and associated genes in fragrant cyclamen 131 6.5 Mutagenesis and screening 133 6.6 Genetic background and the obtained mutants 136 6.7 Carnations with peculiar glittering colors 137 6.8 Conclusion 139 Acknowledgments 140 References 140 7 Flavonols Regulate Plant Growth and Development through Regulation of Auxin Transport and Cellular Redox Status 143 Sheena R. Gayomba, Justin M. Watkins and Gloria K. Muday 7.1 Introduction 143 7.2 The flavonoids and their biosynthetic pathway 144 7.3 Flavonoids affect root elongation and gravitropism through alteration of auxin transport 146 7.4 Mechanisms by which flavonols regulate IAA transport 149 7.5 Lateral root formation 151 7.6 Cotyledon, trichome, and root hair development 152 7.7 Inflorescence architecture 154 7.8 Fertility and pollen development 154 7.9 Flavonols modulate ROS signaling in guard cells to regulate stomatal aperture 155 7.10 Transcriptional machinery that controls synthesis of flavonoids 157 7.11 Hormonal controls of flavonoid synthesis 160 7.12 Flavonoid synthesis is regulated by light 161 7.13 Conclusions 162 Acknowledgments 163 References 163 8 Structure of Polyacylated Anthocyanins and Their UV Protective Effect 171 Kumi Yoshida, Kin-ichi Oyama and Tadao Kondo 8.1 Introduction 171 8.2 Occurrence and structure of polyacylated anthocyanins in blue flowers 173 8.3 Molecular associations of polyacylated anthocyanins in blue flower petals 178 8.4 UV protection of polyacylated anthocyanins from solar radiation 183 8.5 Conclusion 187 References 188 9 The Involvement of Anthocyanin-Rich Foods in Retinal Damage 193 Kenjirou Ogawa and Hideaki Hara 9.1 Introduction 193 9.2 Anthocyanin-rich foods for eye health 195 9.3 Experimental models to mimic eye diseases and the effect of anthocyanin-rich foods 196 9.4 Conclusions 201 References 203 10 Prevention and Treatment of Diabetes Using Polyphenols via Activation of AMP-Activated Protein Kinase and Stimulation of Glucagon-like Peptide-1 Secretion 206 Takanori Tsuda 10.1 Introduction 206 10.2 Activation of AMPK and metabolic change 207 10.3 GLP-1 action and diabetes prevention/suppression 212 10.4 Future issues and prospects 220 References 222 11 Beneficial Vascular Responses to Proanthocyanidins: Critical Assessment of Plant-Based Test Materials and Insight into the Signaling Pathways 226 Herbert Kolodziej 11.1 Introduction 227 11.2 Appraisal of test materials 228 11.3 Endothelial dysfunction 233 11.4 In vitro test systems 234 11.5 Vasorelaxant mechanisms 235 11.6 Bioavailability and metabolic transformation: the missing link in the evidence to action in the body 249 11.7 Conclusions 250 References 251 12 Polyphenols for Brain and Cognitive Health 259 Katherine H. M. Cox and Andrew Scholey 12.1 Introduction 259 12.2 Studies of total polyphenols and cognition 260 12.3 Pine bark 272 12.4 Discussion and conclusions 283 References 283 13 Curcumin and Cancer Metastasis 289 Ikuo Saiki 13.1 Introduction 290 13.2 Effects of curcumin on intra-hepatic metastasis of liver cancer 293 13.3 Effects of curcumin on lymp node metastasis of lung cancer 298 13.4 Effects of curcumin on tumor angiogenesis 303 13.5 Conclusions 307 References 307 14 Phytochemical and Pharmacological Overview of Cistanche Species 313 Hai-Ning Lv, Ke-Wu Zeng, Yue-Lin Song, Yong Jiang and Peng-Fei Tu 14.1 Introduction 313 14.2 Chemical constituents of Cistanche species 314 14.3 Bioactivities of the extracts and pure compounds from Cistanche species 322 14.4 Conclusions 334 References 334 Index 342
Contributors xv Preface xix 1 The Physical Chemistry of Polyphenols: Insights into the Activity of Polyphenols in Humans at the Molecular Level 1 Olivier Dangles, Claire Dufour, Claire Tonnelé and Patrick Trouillas 1.1 Introduction 1 1.2 Molecular complexation of polyphenols 4 1.3 Polyphenols as electron donors 11 1.4 Polyphenols as ligands for metal ions 21 1.5 Conclusions 27 References 28 2 Polyphenols in Bryophytes: Structures, Biological Activities, and Bio- and Total Syntheses 36 Yoshinori Asakawa 2.1 Introduction 36 2.1 Distribution of cyclic and acyclic bis-bibenzyls in Marchantiophyta (liverworts) 37 2.3 Biosynthesis of bis-bibenzyls 39 2.4 The structures of bis-bibenzyls and their total synthesis 50 2.5 Biological activity of bis-bibenzyls 58 2.6 Conclusions 60 Acknowledgments 61 References 61 3 Oxidation Mechanism of Polyphenols and Chemistry of Black Tea 67 Yosuke Matsuo and Takashi Tanaka 3.1 Introduction 67 3.2 Catechin oxidation and production of theaflavins 71 3.3 Theasinensins 73 3.4 Coupled oxidation mechanism 75 3.5 Bicyclo[3.2.1]octane intermediates 77 3.6 Structures of catechin oxidation products 78 3.7 Oligomeric oxidation products 82 3.8 Conclusions 84 Acknowledgments 85 References 85 4 A Proteomic-Based Quantitative Analysis of the Relationship Between Monolignol Biosynthetic Protein Abundance and Lignin Content Using Transgenic Populus trichocarpa 89 Jack P. Wang, Sermsawat Tunlaya-Anukit, Rui Shi, Ting-Feng Yeh, Ling Chuang, Fikret Isik, Chenmin Yang, Jie Liu, Quanzi Li, Philip L. Loziuk, Punith P. Naik, David C. Muddiman, Joel J. Ducoste, Cranos M. Williams, Ronald R. Sederoff and Vincent L. Chiang 4.1 Introduction 90 4.2 Results 94 4.3 Discussion 101 4.4 Materials and methods 102 References 104 5 Monolignol Biosynthesis and Regulation in Grasses 108 Peng Xu and Laigeng Li 5.1 Introduction 108 5.2 Unique cell walls in grasses 109 5.3 Lignin deposition in grasses 110 5.4 Monolignol biosynthesis in grasses 111 5.5 Regulation of monolignol biosynthesis in grasses 114 5.6 Remarks 119 Acknowledgments 119 References 120 6 Creation of Flower Color Mutants Using Ion Beams and a Comprehensive Analysis of Anthocyanin Composition and Genetic Background 127 Yoshihiro Hase 6.1 Introduction 127 6.2 Induction of flower color mutants by ion beams 129 6.3 Mutagenic effects and the molecular nature of the mutations 131 6.4 Comprehensive analyses of flower color, pigments, and associated genes in fragrant cyclamen 131 6.5 Mutagenesis and screening 133 6.6 Genetic background and the obtained mutants 136 6.7 Carnations with peculiar glittering colors 137 6.8 Conclusion 139 Acknowledgments 140 References 140 7 Flavonols Regulate Plant Growth and Development through Regulation of Auxin Transport and Cellular Redox Status 143 Sheena R. Gayomba, Justin M. Watkins and Gloria K. Muday 7.1 Introduction 143 7.2 The flavonoids and their biosynthetic pathway 144 7.3 Flavonoids affect root elongation and gravitropism through alteration of auxin transport 146 7.4 Mechanisms by which flavonols regulate IAA transport 149 7.5 Lateral root formation 151 7.6 Cotyledon, trichome, and root hair development 152 7.7 Inflorescence architecture 154 7.8 Fertility and pollen development 154 7.9 Flavonols modulate ROS signaling in guard cells to regulate stomatal aperture 155 7.10 Transcriptional machinery that controls synthesis of flavonoids 157 7.11 Hormonal controls of flavonoid synthesis 160 7.12 Flavonoid synthesis is regulated by light 161 7.13 Conclusions 162 Acknowledgments 163 References 163 8 Structure of Polyacylated Anthocyanins and Their UV Protective Effect 171 Kumi Yoshida, Kin-ichi Oyama and Tadao Kondo 8.1 Introduction 171 8.2 Occurrence and structure of polyacylated anthocyanins in blue flowers 173 8.3 Molecular associations of polyacylated anthocyanins in blue flower petals 178 8.4 UV protection of polyacylated anthocyanins from solar radiation 183 8.5 Conclusion 187 References 188 9 The Involvement of Anthocyanin-Rich Foods in Retinal Damage 193 Kenjirou Ogawa and Hideaki Hara 9.1 Introduction 193 9.2 Anthocyanin-rich foods for eye health 195 9.3 Experimental models to mimic eye diseases and the effect of anthocyanin-rich foods 196 9.4 Conclusions 201 References 203 10 Prevention and Treatment of Diabetes Using Polyphenols via Activation of AMP-Activated Protein Kinase and Stimulation of Glucagon-like Peptide-1 Secretion 206 Takanori Tsuda 10.1 Introduction 206 10.2 Activation of AMPK and metabolic change 207 10.3 GLP-1 action and diabetes prevention/suppression 212 10.4 Future issues and prospects 220 References 222 11 Beneficial Vascular Responses to Proanthocyanidins: Critical Assessment of Plant-Based Test Materials and Insight into the Signaling Pathways 226 Herbert Kolodziej 11.1 Introduction 227 11.2 Appraisal of test materials 228 11.3 Endothelial dysfunction 233 11.4 In vitro test systems 234 11.5 Vasorelaxant mechanisms 235 11.6 Bioavailability and metabolic transformation: the missing link in the evidence to action in the body 249 11.7 Conclusions 250 References 251 12 Polyphenols for Brain and Cognitive Health 259 Katherine H. M. Cox and Andrew Scholey 12.1 Introduction 259 12.2 Studies of total polyphenols and cognition 260 12.3 Pine bark 272 12.4 Discussion and conclusions 283 References 283 13 Curcumin and Cancer Metastasis 289 Ikuo Saiki 13.1 Introduction 290 13.2 Effects of curcumin on intra-hepatic metastasis of liver cancer 293 13.3 Effects of curcumin on lymp node metastasis of lung cancer 298 13.4 Effects of curcumin on tumor angiogenesis 303 13.5 Conclusions 307 References 307 14 Phytochemical and Pharmacological Overview of Cistanche Species 313 Hai-Ning Lv, Ke-Wu Zeng, Yue-Lin Song, Yong Jiang and Peng-Fei Tu 14.1 Introduction 313 14.2 Chemical constituents of Cistanche species 314 14.3 Bioactivities of the extracts and pure compounds from Cistanche species 322 14.4 Conclusions 334 References 334 Index 342
Es gelten unsere Allgemeinen Geschäftsbedingungen: www.buecher.de/agb
Impressum
www.buecher.de ist ein Internetauftritt der buecher.de internetstores GmbH
Geschäftsführung: Monica Sawhney | Roland Kölbl | Günter Hilger
Sitz der Gesellschaft: Batheyer Straße 115 - 117, 58099 Hagen
Postanschrift: Bürgermeister-Wegele-Str. 12, 86167 Augsburg
Amtsgericht Hagen HRB 13257
Steuernummer: 321/5800/1497
USt-IdNr: DE450055826
