Reproductomics (eBook, ePUB)

The -Omics Revolution and Its Impact on Human Reproductive Medicine
Redaktion: Horcajadas, José A.; Gosálvez, Jaime

• Format: ePub

Produktbeschreibung

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The -Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance.

With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine.

• Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine
• Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data
• Features chapter contributions by leading international experts

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 425
• Erscheinungstermin: 13. Juli 2018
• Englisch
• ISBN-13: 9780128126769
• Artikelnr.: 50474385

Autorenporträt

Jose Horcajadas, PhD, is Associate Professor at the University Pablo de Olavide, Sevilla, Spain. Dr. Horcajadas is an expert in translational research with emphasis on human implantation. He has more than 50 publications in high-impact peer reviewed journals including The Journal of Endocrinology and Metabolism. For the past 3 years Dr. Horcajadas has been an active collaborator in the development of a three-dimensional endometrial culture system at The Jones Institute, which has resulted in several significant publications and presentations. Dr. Horcajadas has also presented at various national and international meetings.

Inhaltsangabe

1. Is the classic spermiogram still informative? How did it develop and where is it going?
2. Genetics variations and male infertility
3. Genetic Variations and Male Infertility
4. Carrier Screening for Inherited Genetic Disorders: A Review of Current Practices
5. TELOMERES IN GERMLINE AND EARLY EMBRYO- AN OVERVIEW
6. Human Protamine Genes' Polymorphisms As A Possible Cause Underlying Male Infertility
7. Small RNAs present in semen and their role in reproduction
8. ALTERED TRANSCRIPTOMIC PROFILES ASSOCIATED WITH MALE INFERTILITY
9. Proteomics and metabolomics studies and clinical outcomes
10. Epigenetics, spermatogenesis and male infertility
11. Changes in DNA methylation related to male infertility
12. Non-invasive methods of embryo selection
13. Genetic selection of the human embryos: from FISH to NGS, past and future
14. Unraveling the causes of failed fertilization after intracytoplasmic sperm injection due to oocyte activation deficiency
15. The molecular signature of the endometrial receptivity: research and clinical application
16. The acquisition of the human endometrial receptivity phenotype: lessons from proteomic studies
17. Stem Cell Derived Spermatozoa
18. Computational approaches in Reproductomics
19. Year 2020: The "-Omics Technologies and Personalized Assisted Reproduction