Retinal and Choroidal Angiogenesis (eBook, PDF)

Redaktion: Penn, John

• Format: PDF

Produktbeschreibung

This book provides a comprehensive, in-depth review of our current understanding of the growth of blood vessels within the eye. Novel therapeutic strategies for the treatment of ocular angiogenesis are discussed, as are the unique challenges presented by delivery of drugs to the eye. The book emphasizes basic principles rather than specific experimental results, although recently acquired data is frequently cited to illustrate points of broader theoretical significance.

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Produktdetails

• Verlag: Springer Netherlands
• Seitenzahl: 557
• Erscheinungstermin: 19. Januar 2008
• Englisch
• ISBN-13: 9781402067808
• Artikelnr.: 37348932

Inhaltsangabe

Angiogenesis Study Models.- Cellular and Molecular Mechanisms of Retinal Angiogenesis.- Animal Models of Choroidal Neovascularization.- Rodent Models of Oxygen-Induced Retinopathy.- Animal Models of Diabetic Retinopathy.- Neovascularization in Models of Branch Retinal Vein Occlusion.- Molecular Characterization.- Vasculogenesis and Angiogenesis in Formation of the Human Retinal Vasculature.- IGF-1 and Retinopathy.- Hypoxia and Retinal Neovascularization.- Hypoxia Inducible Factor-1 and VEGF Induction.- The Role of Protein Kinase C in Diabetic Retinal Vascular Abnormalities.- Eph Receptor Tyrosine Kinases: Modulators of Angiogenesis.- Adenosine in Retinal Vasculogenesis and Angiogenesis in Oxygen-Induced Retinopathy.- The Regulation of Retinal Angiogenesis by Cyclooxygenase and the Prostanoids.- Extracellular Proteinases in Ocular Angiogenesis.- Oxygen-Independent Angiogenic Stimuli.- Growth Factor Synergy in Angiogenesis.- Pigment Epithelium-Derived Factor and Angiogenesis.- Circulating Endothelial Progenitor Cells and Adult Vasculogenesis.- Applications to Clinical Conditions.- Retinopathy of Prematurity.- Angiogenesis in Sickle Cell Retinopathy.- Diabetic Retinopathy.- Systems for Drug Delivery to the Posterior Segment of the Eye.- Novel Therapeutic Strategies For Posterior Segment Neovascularization.- Choroidal Neovascularization in Age-Related Macular Degeneration-From Mice to Man.