Retinal Degenerations (eBook, PDF)

Biology, Diagnostics, and Therapeutics
Redaktion: Tombran-Tink, Joyce; Barnstable, Colin J.

• Format: PDF

Produktbeschreibung

This book presents new and noteworthy research into retinal diseases.

It focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision. Written by renowned scientific investigators, this innovative collection of treatment strategies and technological discoveries allows for the realistic translation of research into practice.

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Produktdetails

• Verlag: Humana Press
• Seitenzahl: 466
• Erscheinungstermin: 6. November 2007
• Englisch
• ISBN-13: 9781597451864
• Artikelnr.: 52637924

Autorenporträt

Joyce Tombran-Tink, University of Missouri-Kansas City, Kansas City, MO, USA / Colin J. Barnstable, Yale University, School of Medicine, New Haven, CT, USA

Inhaltsangabe

Living with Retinal Degeneration.- Coping With Retinal Degeneration.- Degenerative Diseases of the Retina.- Epidemiology of Age-Related Macular Degeneration Early in the 21st Century.- Leber Congenital Amaurosis.- Macular Degeneration.- Stargardt Disease.- X-Linked Juvenile Retinoschisis.- Retinal Degeneration in Usher Syndrome.- Mouse Models of RP.- Mechanisms Underlying Retinal Degenerations.- The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina.- Statins and Age-Related Maculopathy.- The Role of Drusen in Macular Degeneration and New Methods of Quantification.- RPE Lipofuscin.- Genetic Modifiers That Affect Phenotypic Expression of Retinal Diseases.- X-Linked Retinal Dystrophies and Microtubular Functions Within the Retina.- Synaptic Remodeling in Retinal Degeneration.- Developing Therapeutic Strategies for Retinal Degenerative Diseases.- On The Suppression of Photoreceptor Cell Death in Retinitis Pigmentosa.- Cell-Based Therapies to Restrict the Progress of Photoreceptor Degeneration.- Current Status of IPE Transplantation and Its Potential as a Cell-Based Therapy for Age-Related Macular Degeneration and Retinal Dystrophies.- Recent Results in Retinal Transplantation Give Hope for Restoring Vision.- Stem Cells and Retinal Transplantation.- Application of Encapsulated Cell Technology for Retinal Degenerative Diseases.- Effective Treatment for the Canine RPE65 Null Mutation, a Hereditary Retinal Dystrophy Comparable to Human Leber's Congenital Amaurosis.- Neuroprotective Factors and Retinal Degenerations.- Carbonic Anhydrase Inhibitors as a Possible Therapy for RP17, an Autosomal Dominant Retinitis Pigmentosa Associated With the R14W Mutation, Apoptosis, and the Unfolded Protein Response.- Macular Degeneration-An Addendum.

Rezensionen

From the reviews:

"This book is a comprehensive review of the retinal degenerations, focusing particularly on a range of macular degenerations and the inherited retinal dystrophies. ... is essential reading for even the experienced low vision clinician and anyone wishing to understand the difficulties faced by patients who are diagnosed with sight-threatening retinal conditions. ... will be of interest to research groups. ... This is a valuable book and is essential for low vision clinicians. I recommend it to any optometrist with a particular interest in retinal disease." (Michael Kalloniatis, Clinical and Experimental Optometry, Issue 91, November, 2008)