Rheumatic Diseases (eBook, PDF)

Immunological Mechanisms and Prospects for New Therapies
Redaktion: Gaston, J. S. H.

• Format: PDF

Produktbeschreibung

This authoritative review volume provides a wide-ranging account of the immunological mechanisms that underlie many rheumatic diseases. Advances in our understanding of the immunopathology of diseases such as rheumatoid arthritis, ankylosing spondylitis and SLE, are paving the way for the development of effective and rational new therapies. This exciting prospect is an important stimulus for ground-breaking research into these diseases and the investigation of new therapeutic options. As the first book to focus exclusively on this burgeoning area of clinical research, this is an invaluable and contemporary account for all rheumatologists, clinical immunologists and those seeking to develop effective new therapies to combat rheumatic diseases.

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Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 28. Juli 1999
• Englisch
• ISBN-13: 9780511059599
• Artikelnr.: 38206006

Inhaltsangabe

Implications of advances in immunology for understanding the pathogenesis
and treatment of rheumatic disease J. S. Hill Gaston; 1. The role of T
cells in autoimmune disease R. J. Moots and K. W. Wucherpfennig; 2. The
role of MHC antigens in autoimmunity J. H. Buckner and G. T. Nepom; 3. B
cells - formation and structure of autoantibodies A. Rahman, F. K.
Stevenson and D. A. Isenberg; 4. Role of CD40 in immune responses P. Lane;
5. Manipulation of the T cell immune system via CD28 and CTLA-4 D. M.
Samson and L. S. K. Walker; 6. Lymphocyte antigen receptor signal
transduction D. R. Alexander; 7. Role of adhesion mechanisms in
inflammation C. Pitzalis; 8. Regulation of apoptosis in rheumatic disorders
J. McNally, A. K. Vaishnaw and K. B. Elkon; 9. The role of monokines in
arthritisW. B. van den Berg and F. J. J. van de Loo; 10. T lymphocyte sub
sets in relation to autoimuune disease F. Ramirez, B. Seddon and D. Mason;
11. Complement receptors J. M. Ahearn and A. M. Rosengard; Index.