Rhinovirus Infections (eBook, ePUB)

Rethinking the Impact on Human Health and Disease
Redaktion: Bartlett, Nathan; Knight, Darryl; Wark, Peter

• Format: ePub

Produktbeschreibung

Rhinovirus Infections: Rethinking the Impact on Human Health and Disease provides a timely review of the impact of rhinovirus infections on human health. It identifies disease mechanisms relating to the virus, human host and environmental factors. This viewpoint allows us to look forward to the development of treatments for a virus for which treatment options are currently non-existent. By providing detailed insights into this virus, its host and the environmental factors that play into rhinovirus induced diseases, this book explains disease mechanisms and summarizes existing and developing therapeutic approaches for better research, diagnosis and potential treatments.

• Provides insight into viral diversity and identification of virulence factors, showing how the subtype of rhinovirus affects susceptibility to diseases
• Explores host and environmental factors, explaining how age, health status, genotype, lifestyle and environment influence the outcome of a rhinovirus infection
• Covers vaccines and treatments, discussing the health burden associated with rhinovirus infections and the driving development of an increasing array of treatment approaches

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 314
• Erscheinungstermin: 12. Juni 2019
• Englisch
• ISBN-13: 9780128164181
• Artikelnr.: 56967128

Autorenporträt

A/Prof Bartlett trained as a virologist, first at the University of Oxford and then at Imperial College London. It was at Imperial, based in the National Heart and Lung Institute, that his research became squarely focused on the disease burden associated with rhinovirus infections. At that time pre-clinical models of rhinovirus infection and disease were limited so much of his research was devoted to addressing this deficit. This led to development of in vivo rhinovirus infection models that are now an essential research tool for rhinovirus research worldwide. Following his return to Australia he accepted an academic appointment at the University of Newcastle and formed the Viral Immunology and Respiratory Disease group, based at the Hunter Medical Research Institute (Newcastle, Australia). Since that time A/Prof Bartlett has consolidated his position as an internationally recognised expert on rhinovirus pre-clinical models and disease mechanisms and is currently involved in deve

lopment and commercialisation of multiple new therapies aimed at preventing the plethora of diseases caused by rhinovirus infections. He is also an associate editor for the American Journal of Physiology - Lung Molecular and Cellular Physiology and member of the College of Experts for the European Respiratory Society.

Inhaltsangabe

1. Rhinovirus classification, structure and replication 2. Diversity and virulence factors 3. Ground zero - the airway epithelium 4. Immunity to rhinovirus 5. Rhinovirus infections in early life 6. Exacerbations of chronic respiratory diseases 7. Interplay of host, virus and environment 8. Experimental models of infection and disease 9. Emerging therapeutic approaches 10. Techniques for detection and research