Systemic sclerosis is a chronic autoimmune disease with a complex pathophysiology and potential involvement of multiple organs. The second edition of this textbook gives a practically oriented overview on epidemiology, pathophysiology, classification, disease manifestations and treatment options. Particular attention is paid to novel developments in the classification criteria, molecular targets for therapy and recently approved treatments for organ manifestations. It gives a comprehensive overview for both the experienced clinician and younger colleagues.
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