William D. Willis Jr.

Sensory Mechanisms of the Spinal Cord (eBook, PDF)

• Format: PDF

Produktbeschreibung

As stated in the preface to the first edition, the goal of this monograph is to provide an overview of current thought about the spinal cord mechanisms responsible for sensory processing. We hope that the book will be of value to both basic neuroscientists and clinicians. The organization of the monograph has followed the original plan in most respects, although the emphasis has changed with respect to many topics because of recent advances. In particular, a substantial increase in the number of investigations of the dorsal root ganglion has led us to devote a chapter to this topic. The treatment of chemical neuroanatomy in the dorsal horn, as well as the relevant neuropharmacology, has also been expanded considerably. Another major emphasis is on the results of experiments employing microneurography in human subjects. We thank Margie Watson and Lyn Schilling for their assistance with the typing and Griselda Gonzales for preparing the illustrations.

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 575
• Erscheinungstermin: 29. Juni 2013
• Englisch
• ISBN-13: 9781489905970
• Artikelnr.: 44173823

Inhaltsangabe

1: Introduction.- Sensory Modalities and Channels.- Specificity versus Pattern Theories of Sensation.- Somatosensory System Dualities.- Conclusions.- 2: Sensory Receptors and Peripheral Nerves.- Composition of Peripheral Nerves.- Sensory Receptors.- Cutaneous Receptors.- Muscle Receptors.- Joint Receptors.- Visceral Receptors.- Conclusions.- 3: Dorsal Root Ganglion Cells and their Processes.- Dorsal Root Ganglion Cell Bodies.- Dorsal Root Ganglion Cell Processes.- Conclusions.- 4: Chemical Anatomy of Dorsal Root Ganglion Cells.- Amines.- Amino Acids.- Channels.- Enzymes.- Hormones.- Peptides.- VIP.- Proteins.- Receptors.- Conclusions.- 5: Structure of the Dorsal Horn.- Lamina I.- Lamina II (The Substantia Gelatinosa).- Lamina III.- Lamina IV.- Lamina V.- Lamina VI.- Conclusions.- 6: Chemical Anatomy of the Dorsal Horn.- Amines.- Amino Acids.- Channels.- Enzymes.- Hormones.- Peptides.- Opioids.- Proteins.- Receptors.- Conclusions.- 7: Functional Organization of Dorsal Horn Interneurons.- Electrophysiological Recordings from Interneurons.- Population Responses.- Afferent Projections to the Dorsal Horn.- Responses to Electrical Stimulation.- Responses to Natural Stimulation.- Classification of Dorsal Horn Interneurons.- Dorsal Horn Neurons in Unanesthetized, Behaving Animals.- Pharmacology of Dorsal Horn Interneurons.- Inhibitory Transmitters in the Dorsal Horn.- Modulation of the Responses of Dorsal Horn Neurons.- Inhibitory Receptive Fields.- Models of Human Disease.- Genetic Influences on Spinal Cord Sensory Processing.- Conclusions.- References.

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1: Introduction.
2: Sensory Receptors and Peripheral Nerves.
3: Dorsal Root Ganglion Cells and their Processes.
4: Chemical Anatomy of Dorsal Root Ganglion Cells.
5: Structure of the Dorsal Horn.
6: Chemical Anatomy of the Dorsal Horn.
7: Functional Organization of Dorsal Horn Interneurons.
8: Ascending Sensory Pathways in Cord White Matter.
9: Sensory Pathways in the Dorsal Funiculus.
10: Sensory Pathways in the Dorsal Lateral Funiculus.
11: Sensory Pathways in the Ventral Quadrant.
12: The Sensory Channels.
References.

Rezensionen

about the first edition:
`it should prove invaluable for those preparing for teaching and as a base for those wishing to undertake more specialized reading. There is a wealth of hard data which should be the concern equally o fthose interested in any aspect of sensation, including the analysis of pain mechanisms, and of those more interested in the spinal cord as a machine for motor processing.'
Neuroscience