Epiphany Wright, Keisha Moore, and Shana Scott spent their teenage years as best friends in the hood of south side Jamaica, Queens. As adults, their friendship is put to the test when envy, built-up animosity, hidden betrayal, and the bad boys in their lives cause more havoc. Every day becomes a struggle to keep it tight. With all that's riding against them when drastic situations occur, will these girls be down for one another, or be just plain Sheisty?