Beginning with the molecular mechanisms of vertebrate phototransduction, this volume presents the structure of phototransduction cascade components at atomic resolution, as well as molecular interactions in multi-protein complexes and novel cell-based strategies for understanding signal shut-off and light adaptation. It discusses non-visual phototransduction and the role of melanopsin in adaptive photoresponses and circadian clock regulation. It also compares the visual signaling processes of vertebrates and invertebrates, examines studies of insulin-based signaling; investigates signaling in progenitor cells, cell-cell communication in developing cells, and neovascularization; and discusses lipid-derived mediators as well as the participation of retinal pigment epithelium in neuronal survival.
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