Dmitrii E. Makarov

Single Molecule Science (eBook, PDF)

Physical Principles and Models

• Format: PDF

Produktbeschreibung

The observation and manipulation of individual molecules is one of the most exciting developments in modern molecular science, and the utility of single-molecule methods has proven invaluable in such fields as nanoscience and molecular biology. This book provides a general framework necessary for understanding single-molecule phenomena. It introduces the relevant mathematical and physical concepts, and then discusses various approaches to the problem of interpreting single-molecule data. It thoroughly explains the physical principles underlying the major classes of single-molecule experiments, such as fluorescence measurements, force-probe spectroscopy, and nanopore experiments.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 214
• Erscheinungstermin: 9. Juni 2015
• Englisch
• ISBN-13: 9781466559523
• Artikelnr.: 42941362

Autorenporträt

Dmitrii E. Makarov is a professor of chemistry at the University of Texas at Austin. He earned a PhD in theoretical physics from the Institute of Chemical Physics in Moscow. His expertise is in theoretical and computational chemical physics and in biophysics.

Inhaltsangabe

A Brief History of Thought and Real Single-Molecule Experiments. How the
Properties of Individual Molecules Are Measured. The Kinetics of Chemical
Reactions: Single-Molecule Versus "Bulk" View. How Molecules Explore their
Energy Landscapes. Microscopic View of the Rate of a Chemical Reaction: A
Single-Molecule Perspective. Molecular Transition Paths: Why Going Uphill
May Be Faster. Properties of Light Emitted by a Single Molecule and What It
Can Tell Us About Molecular Motion. Single-Molecule Mechanics.
Nonequilibrium Thermodynamics of Single Molecules: The Jarzynski and Crooks
Identities. Single-Molecule Phenomena in Living Systems. Appendix A
Probability Theory, Random Numbers and Random Walks. Appendix B Appendix B:
Elements of Statistical Mechanics.