Single-particle Cryo-EM of Biological Macromolecules (eBook, ePUB)

Redaktion: Glaeser, Robert M; Chiu, Wah; Nogales, Eva

• Format: ePub

Produktbeschreibung

This edited book is written for students, postdocs and established investigators who want to enter the field of single-particle cryo-EM. This is a recently developed method to determine high-resolution structures of biological macromolecules. A major strength is the fact that cryo-EM does not require prior crystallization of protein complexes. Furthermore, it is especially well suited for larger complexes and molecular machines, although it can also be used for macromolecules as small as 40 kDa or less. It also is especially well-suited to deliver high-resolution structural information about multiple conformational states.

Authors of individual sections of this book have been recruited from among the most authoritative leaders in each topic. As a result, this book provides a comprehensive and authoritative coverage of key topics involving theory, data collection, data analysis and validation of results. The co-editors are well-recognized and highly respected leaders in the field of cryo-EM, active members of the Biophysical Society, and members of the US National Academy of Science.

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Produktdetails

• Verlag: Institute of Physics Publishing
• Seitenzahl: 120
• Erscheinungstermin: 19. Mai 2021
• Englisch
• ISBN-13: 9780750330398
• Artikelnr.: 61962114