H. John Smith, Hywel Williams

Smith and Williams' Introduction to the Principles of Drug Design and Action (eBook, ePUB)

• Format: ePub

Produktbeschreibung

As knowledge of biological systems and the number of techniques available for exploring and visualizing their components has increased, it has become possible to design drugs specifically for a given target. Smith and Williams Introduction to the Principles of Drug Design and Action, Fourth Edition provides the basic principles of rational drug design, including both novel and established approaches. This new edition adopts a from-bench-to-marketplace approach, using real examples where possible. It offers a comprehensive update of the previous edition, particularly with respect to new advances in molecular techniques, biotechnological applications, and computer-aided design.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 720
• Erscheinungstermin: 10. Oktober 2005
• Englisch
• ISBN-13: 9781135299750
• Artikelnr.: 57416577

Autorenporträt

H. John Smith, Hywel Williams

Inhaltsangabe

Processes of Drug Handling by the Body. The Design of Drug Delivery
Systems. Fundamental Pharmacokinetics. Intermolecular Forces and Molecular
Modeling. Drug Chirality and its Pharmacological Consequences. Quantitative
Structure-Activity Relationships (QSAR) in Drug Design. Prodrugs. From
Program Sanction to Clinical Trials: A Partial View of the Quest for
Arimidex, A Potent, Selective Inhibitor of Aromatase. Design of Enzyme
Inhibitors as Drugs. Peptide Drug Design. Combinatorial Chemistry: A Tool
for Drug Discovery. Recombinant DNA Technology: Monoclonal Antibodies. The
Human Genome and its Impact on Drug Discovery and Therapy. The Chemotherapy
of Cancer. Neurotransmitters, Agonists, and Antagonists. Design of
Antibacterial, Antifungal, and Antiviral Agents. Pharmaceutical
Applications of Bioinorganic Chemistry. Index.