Spatially Fractionated, Microbeam and FLASH Radiation Therapy (eBook, ePUB)

A physics and multi-disciplinary approach
Redaktion: Zhang, Hualin; Mayr, Nina

• Format: ePub

Produktbeschreibung

Spatially fractionated radiation therapy (SFRT), the concept of treating tumors by delivering a spatially modulated dose with highly non-uniform dose distributions, is an area of rapid development and high interest in radiation oncology, physics and tumor biology. Clinical experience in SFRT suggests high response and low toxicity in the treatment of challenging advanced and bulky tumors. Clinical outcome data is rapidly accumulating while SFRT technologies and techniques are continuously evolving. Initially limited to GRID therapy using metal alloy block collimators, advanced and versatile multi-leaf collimators and volumetric modulated arc technologies have since broadened the capabilities and individualization of SFRT and have expanded the clinical investigators of SFRT to various dosing regimens, multiple malignancies, tumor types and disease sites.

Meanwhile the concepts of spatial fractionation are evolving and beginning to be applied to many different beam types. Microbeam radiation therapy that has recently emerged, leverages rapid developments of synchrotron technologies, as has proton accelerator Minibeam technology, and these technologies are expanding SFRT platforms. This book introduces SFRT, Microbeam, Minibeam and FLASH radiation therapy from the physics, biology, clinical and engineering perspective with chapters contributed by eminent experts in these fields to proved an up-to-date cutting edge-foundation on the principles of heterogeneous radiation, and physics, technical and clinical experience.

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Produktdetails

• Verlag: Institute of Physics Publishing
• Seitenzahl: 250
• Erscheinungstermin: 29. Juni 2023
• Englisch
• ISBN-13: 9780750340465
• Artikelnr.: 68370121