Sperm Cell (eBook, ePUB)

Production, Maturation, Fertilization, Regeneration
Redaktion: Jonge, Christopher J. de

• Format: ePub

Produktbeschreibung

This revised and updated second edition provides a comprehensive account of the human male gamete. Detailed overviews of human sperm production, maturation, and function - and how these processes affect and influence fertility, infertility, and assisted reproduction - are given. A wide range of new developments including proteomics, spermatogenesis, sperm-specific WW domain-binding proteins, Ca2+ signalling, DNA packaging, epididymis are explored, whilst a new chapter presents information gained from mouse genetics, highlighting how it informs male fertility research. The impact of environmental factors during pre-pubertal and pubertal stages of life is also investigated. Featuring engaging prose with chapters organized topographically, The Sperm Cell remains an essential resource for andrologists, clinical scientists, and laboratory personnel.

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Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 25. Mai 2017
• Englisch
• ISBN-13: 9781108138291
• Artikelnr.: 49047361

Inhaltsangabe

List of contributors; Foreword Ryuzo Yanagimachi; Preface; 1.
Spermatogenesis: clinical and experimental considerations Ellen Goossens
and Herman Tournaye; 2. Sperm chromatin stability and susceptibility to
damage in relation to its structure W. Steven Ward; 3. Sperm ultrastructure
in fertile men and male sterility: revisiting teratozoospermia Hector E.
Chemes; 4. Sperm RNA and its use as a clinical marker Meritxell Jodar,
Ester Anton and Stephen A. Krawetz; 5. Role of the epididymis in sperm
maturation Robert Sullivan and Clémence Belleannée; 6. Seminal plasma plays
important roles in fertility Susan S. Suarez and Mariana F. Wolfner; 7.
Physiological and pathological aspects of sperm metabolism Zamira Gibb and
Robert John Aitken; 8. Regulation of sperm behaviour: the role(s) of
[Ca2+]i signalling Stephen Publicover; 9. Proteomics of capacitation Mark
A. Baker; 10. Current concepts and unresolved questions in human sperm
cumulus and zona interaction Christopher De Jonge and Christopher L. R.
Barratt; 11. Sperm specific WW-domain binding proteins Richard Oko, Mahmoud
Aarabi, Jiude Mao, Hanna Balakier and Peter Sutovsky; 12. Fundamental role
for sperm phospholipase C zeta at mammalian fertilization Michail Nomikos,
Karl Swann and F. Anthony Lai; 13. Genetic basis of male infertility Amin
S. Herati, Peter R. Butler and Dolores J. Lamb; 14. The Sperm epigenome
Timothy G. Jenkins and Douglas T. Carrell; 15. Environmental factors and
male fertility Tina Kold Jensen, Hanne Frederiksen, Katrine Bay and Niels
E. Skakkebaek; 16. Male infertility and assisted reproduction Nigel
Pereira, Queenie V. Neri, Tyler Cozzubbo, Stephanie Cheung, Zev Rosenwaks
and Gianpiero D. Palermo; 17. Mouse genetics - how does it inform male
fertility research? Laura O'Hara and Lee B. Smith; 18. Susceptibility of
the testis to lifestyle and environmental factors during the life course
Richard M. Sharpe; Index.