Standardizing Pharmacology: Assays and Hormones (eBook, ePUB)

Discoveries in Pharmacology, Volume 2
Redaktion: Parnham, Michael J.; Bruinvels, Jacques; Page BSc

• Format: ePub

Produktbeschreibung

Standardizing Pharmacology: Assays and Hormones, Volume Two in the Discoveries in Pharmacology series, presents selected articles from historic discoveries that are enhanced with commentary from contemporary scholars who present discussions on the importance of each chapter, along with an updated bibliography on the subject and contributions from a Nobel Prize winner and other pioneers in pharmacology. Academic and industry researchers in pharmacology and medicine, as well as advanced students will find this series a useful teaching tool and launch to new discoveries.

Sections cover key discoveries in receptor theory, pharmacological methods and the development of hormone therapy, including J. Parascandola on the development of receptor theory, R.S. Yalow on radioimmunoassay, M. van Rossum and J.T L.A. Hurkmans on bioassays, M. Tausk on androgen therapy and C. Djerassi on oral contraceptives, with commentaries from experts such as T. Hökfelt and V.C. Jordan.

• Contains primary-source documents currently unavailable elsewhere
• Presents the science behind major pharmacological breakthroughs by those who discovered them
• Includes commentary contextualizing the importance of discoveries and related readings

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 284
• Erscheinungstermin: 23. Februar 2023
• Englisch
• ISBN-13: 9780323855181
• Artikelnr.: 67507144

Inhaltsangabe

Section I. Redirected traffic: the history of drugs affecting haemodynamics
1. The control of blood pressure Part 1 - The discovery of beta
adrenoceptor blocking drugs Part 2 - Peripheral anti-hypertensives:
ganglion and adrenergic neurone-blocking agents
Section II. The discovery and application of hormones 2. The emergence of
endocrinology 3. Sex hormones Part 1 - Androgens and anabolic steroids Part
2 - The biological history of the Pill Part 3 - The chemical history of the
Pill
Section III. Overcoming the body's defence system 4. Anti-inflammatory
drugs Part 1 - The proliferation of non-steroidal anti-inflammatory drugs
(NSATDS) Part 2 - The story of aspirin, H.O.J. Collier 5. The inhibition of
allergic reactions Part I - Histamine receptor antagonists Part 2 - Asthma:
a long and continuing story
Section IV. Assays and the molecular basis of drug action 6. A probe for
the fine structures of the body 7. Isolated smooth muscle in pharmacology
Part 1 - The guts of the matter: contribution of studies on smooth muscle
to discoveries in pharmacology Part 2 - Bioassay: a pharmacological
endeavour 8. Making visible the invisible (Recollections of the first
experiences with the histochemical fluorescence method for visualization of
tissue monoamines) 9. Receptors in pharmacology
Section V. History of chemotherapy 10. From dyes to drugs 11. The discovery
of penicillin and cephalosporins 12. The antibiotic explosion