James D. Malley

Statistical Learning for Biomedical Data (eBook, PDF)

• Format: PDF

Produktbeschreibung

This book is for anyone who has biomedical data and needs to identify variables that predict an outcome, for two-group outcomes such as tumor/not-tumor, survival/death, or response from treatment. Statistical learning machines are ideally suited to these types of prediction problems, especially if the variables being studied may not meet the assumptions of traditional techniques. Learning machines come from the world of probability and computer science but are not yet widely used in biomedical research. This introduction brings learning machine techniques to the biomedical world in an accessible way, explaining the underlying principles in nontechnical language and using extensive examples and figures. The authors connect these new methods to familiar techniques by showing how to use the learning machine models to generate smaller, more easily interpretable traditional models. Coverage includes single decision trees, multiple-tree techniques such as Random Forests(TM), neural nets, support vector machines, nearest neighbors and boosting.

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Produktdetails

• Verlag: Cambridge University Press
• Erscheinungstermin: 24. Februar 2011
• Englisch
• ISBN-13: 9780511985546
• Artikelnr.: 38214771

Autorenporträt

James D. Malley is a Research Mathematical Statistician in the Mathematical and Statistical Computing Laboratory, Division of Computational Bioscience, Center for Information Technology, at the National Institutes of Health.

Inhaltsangabe

Preface
Acknowledgements
Part I. Introduction: 1. Prologue
2. The landscape of learning machines
3. A mangle of machines
4. Three examples and several machines
Part II. A Machine Toolkit: 5. Logistic regression
6. A single decision tree
7. Random forests - trees everywhere
Part III. Analysis Fundamentals: 8. Merely two variables
9. More than two variables
10. Resampling methods
11. Error analysis and model validation
Part IV. Machine Strategies: 12. Ensemble methods - let's take a vote
13. Summary and conclusions
References
Index.

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Preface; Acknowledgements; Part I. Introduction: 1. Prologue; 2. The landscape of learning machines; 3. A mangle of machines; 4. Three examples and several machines; Part II. A Machine Toolkit: 5. Logistic regression; 6. A single decision tree; 7. Random forests - trees everywhere; Part III. Analysis Fundamentals: 8. Merely two variables; 9. More than two variables; 10. Resampling methods; 11. Error analysis and model validation; Part IV. Machine Strategies: 12. Ensemble methods - let's take a vote; 13. Summary and conclusions; References; Index.

Rezensionen

'The book is well written and provides nice graphics and numerous applications.' Michael R. Chernick, Technometrics