Structural Bioinformatics (eBook, PDF)

Methods and Protocols
Redaktion: Gáspári, Zoltán

• Format: PDF

Produktbeschreibung

This volume looks at the latest techniques used to perform comparative structure analyses, and predict and evaluate protein-ligand interactions. The chapters in this book cover tools and servers such as LiteMol; Bio3D-Web; DALI; CATH; HoTMuSiC, a contact-base protein structure analysis tool known as CAD-Score; PyDockSaxs and HADDOCK; CombDock and DockStar; the BioMagResBank database; as well as BME and CoNSEnsX+. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, step-by-step, readily reproducible computational protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and comprehensive, Structural Bioinformatics: Methods and Protocols is a practical guide for researchers to learn more about the aforementioned tools to further enhance their studies in the growing field of structural bioinformatics.

Chapter 13 is open access under a CC-BY 4.0 license via link.springer.com.

---

Dieser Download kann aus rechtlichen Gründen nur mit Rechnungsadresse in A, B, BG, CY, CZ, D, DK, EW, E, FIN, F, GR, HR, H, IRL, I, LT, L, LR, M, NL, PL, P, R, S, SLO, SK ausgeliefert werden.

Produktdetails

• Verlag: Springer New York
• Seitenzahl: 256
• Erscheinungstermin: 31. Januar 2020
• Englisch
• ISBN-13: 9781071602706
• Artikelnr.: 64700256

Inhaltsangabe

Visualization and Analysis of Protein Structures with LiteMol Suite.- Comparative Protein Structure Analysis with Bio3D-Web.- Using DALI for Protein Structure Comparison.- Assessing Protein Function through Structural Similarities with CATH.- Protein Thermal Stability Engineering using HoTMuSiC.- Contact Area-Based Structural Analysis of Proteins and their Complexes using CAD-Score.- A Comprehensive Computational Platform to Guide Drug Development using Graph-Based Signature Methods.- Systematic Exploration of Binding Modes of Ligands on Drug Targets.- Using MemBlob to Analyze Transmembrane Regions Based on Cryo-EM Maps.- Structural Characterization of Protein-Protein Interactions with pyDockSAXS.- Protein-Protein Modeling using Cryo-EM Restraints.- Modeling of Multimolecular Complexes.- Biological Assembly Comparison with VAST+.- BioMagResBank (BMRB) as a Resource for Structural Biology.- Integrating MolecularSimulation and Experimental Data: A Bayesian/Maximum Entropy Reweighting Approach.- Evaluation and Selection of Dynamic Protein Structural Ensembles with CoNSEnsX+.