Peter Tompa, Alan Fersht

Structure and Function of Intrinsically Disordered Proteins (eBook, PDF)

• Format: PDF

Produktbeschreibung

A detailed investigation into intrinsically disordered proteins (IDP), this seminal work illustrates how IDPs defy the structure-function paradigm and play important regulatory and signaling roles. Introducing basic terms and fundamental principals of protein science, the author presents a unified theory of ordered and disordered proteins and outlines new applications for traditional biophysical and bioinformatic techniques, such as x-ray crystallography and NMR. The book reviews the structure, function, and evolution of IDPs and considers biomedical implications as well as applications in drug development for cancer and neurodegenerative diseases.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 359
• Erscheinungstermin: 18. November 2009
• Englisch
• ISBN-13: 9781420078930
• Artikelnr.: 57533353

Autorenporträt

Peter Tompa is Group Leader in the Laboratory of Intrinsically Disordered Proteins, Institute of Enzymology, Biological Research Center at the Hungarian Academy of Sciences in Budapest.