System Vaccinology (eBook, ePUB)

The History, the Translational Challenges and the Future
Redaktion: Prajapati, Vijay Kumar

• Format: ePub

Produktbeschreibung

Emergence of new and deadly infectious diseases is significantly deteriorating the human health. Development of vaccine by the scientist has become an important weapon to control the spread of infectious diseases as well as to improve the life expectancy at global level in 20th-21st Century. This book will provide the in-depth knowledge of vaccine history, and development of new strategies to design efficacious and safe vaccine molecule. This book will cover the development of system vaccinology and their applications revolutionize the vaccine discovery. This will provide a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials.

My purpose to write this book to educate the students and researchers with modern development in the field of vaccinology and empowering the researcher with new tools and methodology for developing potential and immunogenic vaccines.

This book will be helpful to solve the curiosity of science and medical background students related with vaccinology and will be helpful to devise a new vaccine molecule to control the spread of new and emerging pathogens.

Systems biology is a rapidly expanding research discipline aiming to integrate multifaceted datasets generated using state-of-the-art high- throughput technologies such as arrays and next-generation sequencing. Combined with sophisticated computational analysis we are able to interrogate host responses to infections and vaccination on a systems level, thus generating important new hypotheses and discovering unknown associations between immunological parameters.

• Provides in-depth knowledge of vaccine history
• Covers the development of system vaccinology and their applications revolutionize the vaccine discovery
• Gives insights to the development of new strategies to design efficacious and safe vaccine molecule
• Provides a resource for the basic and clinical researcher working to human life expectancy by their vaccine experiments and clinical trials
• Highlights the importance of differential miRNA expression, microbiome after vaccination for human health
• Serves the need of students and researcher for applying computational tools and quick designing of potential molecule which may be proposed for vaccine trial
• Take the decisions to perform the kind of experiments for assessment of vaccine immunogenicity
• Aims to understand disease pathogenesis and host responses to infection and vaccination
• Offers a seamless continuum of scientific discovery and vaccine invention

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 436
• Erscheinungstermin: 20. August 2022
• Englisch
• ISBN-13: 9780323897860
• Artikelnr.: 65345901

Autorenporträt

Dr. Vijay Kumar Prajapati is working as an Associate Professor at Department of Biochemistry, University of Delhi South Campus, New Delhi, India. He has extensive experience on Immunotherapy, antibody engineering and vaccine development for infectious diseases. He has published approx. 100 research articles in the international journal with >10 book chapters with reputed publishers. He is a recipient of prestigious INSA Medal for Young Scientist from Indian National Science Academy (INSA) and Associate from Indian Academy of Sciences, Benguluru. He has published research work in the prestigious journal such as Journal of Infectious Diseases, Clinical Infectious Diseases, Scientific Reports, Medicinal Research Review, Journal of Cellular Physiology etc. His current h-index is 41 with 5243 citations. .

Inhaltsangabe

Part I History and Introduction 1. Vaccine: History and its perspective 2. Evolution of human infectious diseases and vaccine

Part II Immunology of Vaccine Designing 3. Omics and databases of vaccine 4. Adjuvant requirement for vaccines 5. Vaccine Engineering and Structural vaccinolog 6. Vaccine and genome 7. Vaccine and transcriptome 8. miRNA and immunization 9. Vaccine and proteome 10. Vaccine and microbiome

Part III Delivery and Vaccine efficacy 11. rDNA technology and vaccines 12. Developing delivery system for vaccines 13. Infection, immunity and vaccine 14. Animal model and vaccines pre-clinical testing 15. Vaccine human clinical trial

Part IV Vaccine future and Ethics 16. Future of system vaccinology 17. Vaccine regulation and ethics