This edited book is the third such compilation containing chapters that represent the research priorities of the Ivane Beritashvili Center of Experimental Biomedicine, which covers the experimental study of fundamental issues in the functioning of physiological (mainly neurophysiological) mechanisms during normal and pathological conditions. The first and second books - "e;Systemic, Cellular and Molecular Mechanisms of Physiological Functions and Their Disorders"e; - published by Nova Science Publishers Inc. in 2015 and 2018, were also devoted to the same general problems. In the present edited book, particular attention is drawn to the study of extremely important processes underlying the basic mechanisms and disorders of various phenomenon of integrative activity of the brain: general behavior, learning and memory, the sleep-wakefulness cycle, regulation of adequate blood supply, hormesis, epilepsy, depression, sleep disorders, pain and analgesia. All of the mentioned processes are studied on the molecular, cellular and systemic levels of their organization. It has to be noted that each chapter, within the collection of works, represents the results of separate, independent studies implemented by different scientific departments of the center.
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