Major advances have been made in key pathways that control tumor progression. This has led to the development of new anticancer agents that can block the activity of proteins involved in neoplastic cell development and proliferation. This volume provides a concise panorama of existing targeted therapies and progress into future anticancer treatments. Topics include targeted agents of immune checkpoints, signal-transduction and stem cell inhibitors, antiangiogenic and vascular-disrupting agents, apoptosis modulators, and tumor profiling for drug development. The book emphasizes the biology behind this new class of drugs and the clinical achievements obtained.
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