Targeting of Drugs 6 (eBook, PDF)

Strategies for Stealth Therapeutic Systems
Redaktion: Gregoriadis, Gregory; McCormack, Brenda

• Format: PDF

Produktbeschreibung

Proceedings of a NATO ASI held in Cape Sounion Beach, Greece, June 24-July 5, 1997

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Produktdetails

• Verlag: Springer US
• Seitenzahl: 302
• Erscheinungstermin: 29. Juni 2013
• Englisch
• ISBN-13: 9781489901279
• Artikelnr.: 44172983

Inhaltsangabe

Interactions between Blood Components and Artificial Surfaces.- The Mononuclear Phagocyte System: Features Relevant to Interactions with Liposomes.- Stealth(TM) Therapeutic Systems: Rationale and Strategies.- Long Circulating Liposomes: Evolution of the Concept.- Sterically Stabilized Immunoliposomes: Formulations for Delivery of Drugs and Genes to Tumor Cells in Vivo..- Pegylation of Liposomes in Cell-Specific Targeting: It Does Not Always Make Sense.- Stealth(TM) Liposomes for the Targeting of Drugs in Cancer Therapy.- Stealth(TM) Liposomes as Carriers of Doxorubicin.- Liposome-Mediated Delivery of Retinoids.- Applications of Liposome Technology to Overcome Multidrug Resistance in Solid Tumors.- Use of Radiolabeled Liposomes for PEG-Liposome-Based Drug Targeting and Diagnostic Imaging Applications.- Diagnostic and Therapeutic Targeting of Infectious and Inflammatory Diseases Using Sterically Stabilized Liposomes.- Biologically Active Ligand-Bearing Polymer-Grafted Liposomes.- Engineering Stealth(TM) Liposome Surfaces: Exercises in Colloid Chemistry Principles.- The Role of Hydration in Stabilization of Liposomes: Resistance to Oxidative Damage of PEG-Grafted Liposomes.- Physicochemical Characterization of DOTAP-Containing Lipoplexes by Fluorescent Probes: Relevance to Lipofection.- Steric Stabilization of Cationic Liposome-DNA Complexes: Influence on Morphology and Transfection Activity.- Polysialic Acids: Potential for Long Circulating Drug, Protein, Liposome and Other Microparticle Constructs.- Tailor-Made Soluble Polymer Carriers.- Development of Novel Technologies for the Synthesis of Biodegradable Pegylated Nanoparticles.- Development of a New Class of Nanoparticles which Avoid Phagocytosis by Inhibiting Complement Activation.- Coating of Nanoparticles withSurfactants: Targeting versus Prolonged Circulation.- Recent Developments and Limitations of Poloxamine-Coated Long-Circulating Particles in Experimental Drug Delivery.- PEG-Coated Nanospheres: Surface Optimization and Therapeutic Applications.- Participants' Photograph.- Contributors.