Textbook of Receptor Pharmacology (eBook, PDF)

Redaktion: Foreman, John C.; Gibb, Alasdair J.; Johansen, Torben

• Format: PDF

Produktbeschreibung

Originating from a renowned course on receptor pharmacology, this text presents in-depth coverage of this rapidly expanding research area. The book combines current understanding of classical quantitative pharmacology and drug-receptor interactions with the basics of receptor structure and signal transduction mechanisms. It focuses on molecular investigation of receptor structure, quantitative functional studies of agonists and antagonists, ligand binding, and signal transduction at the cell membrane. This edition includes updated chapters on receptor structure and signal transduction by G-proteins and tyrosine kinases as well as enhancements to the quantitative treatment of drug-receptor interactions. Several chapters contain problems and worked-out solutions.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 312
• Erscheinungstermin: 10. September 2010
• Englisch
• ISBN-13: 9781420052558
• Artikelnr.: 57150335

Inhaltsangabe

Drug-Receptor Interactions: Classical Approaches to the Study of Drug-Receptor Interactions. Molecular Structure of Receptors: Structure and Function 7-TM G-Protein Coupled Receptors. The Structure of Ligand-Gated Ion Channels. Molecular Structure of Receptor Tyrosine Kinases. Ligand-Binding Studies of Receptors: Direct Measurement of Drug Binding to Receptors. Transduction of the Receptor Signal: Receptors Linked to Ion Channels: Mechanisms of Activation and Block. G-Proteins. Signal Transduction through Protein Tyrosine Kinases. Receptors as Pharmaceutical Targets: Receptors as Pharmaceutical Targets.

Rezensionen

" ... very well written and informative. This edition updates and refines earlier versions of what is an excellent, interesting, and very informative text on receptor pharmacology, but what else would one expect with contributions from such giants in the discipline? This book is ideal for budding pharmacologists and cell physiologists, both at the undergraduate and postgraduate level, who have an interest in receptor structure and function âEUR¦ would also be of value to students and academics of pharmacy, physiology, medicinal chemistry, and related disciplines."
-Chromatographia