The Bipolar Brain (eBook, PDF)

Integrating Neuroimaging and Genetics
Redaktion: Strakowski, Stephen

• Format: PDF

Produktbeschreibung

Bipolar disorder is one of the most common, and disabling, conditions affecting humankind. Each year, millions of individuals struggle with the effects of this illness. Although clinically well recognized for decades, if not centuries, the causes of this condition remain incompletely understood. However, significant technological advances in both neuroimaging and genetic research have revealed clues about the neurophysiological basis of bipolar illness. In this second edition of The Bipolar Brain, leading experts in neuroimaging and genetics discuss recent discoveries in bipolar disorder that identify the structural, functional and chemical brain changes that seem to underlie this condition, as well as the possible genetic causes of these brain events. New technologies such as miRNA, cerebral blood flow, and fMRI are presented. Based upon these discussions, the authors then integrate these diverse considerations to develop a specific neurophysiological model of bipolar disorder. This model provides a resource to guide clinicians as they struggle to understand this illness, as well as a guide for future investigations into the causes of bipolar disorder. With this guide in hand, this book will lead to a new framework for understanding bipolar disorder in order to, ultimately, develop improved therapies for affected individuals and novel strategies to prevent the onset in children at risk for this condition.

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Produktdetails

• Verlag: Oxford University Press
• Erscheinungstermin: 29. März 2022
• Englisch
• ISBN-13: 9780197574539
• Artikelnr.: 63896621

Autorenporträt

Stephen M. Strakowski, MD, is Vice Dean for Research, and Associate Vice President, Regional Mental Health, Dell Medical School, University of Texas at Austin. He is an internationally recognized expert in the management of bipolar disorders, as a Best Doctor® and by US News and World Report® as a Top 1% Psychiatrist. His research focuses on the brain changes that occur at the onset of bipolar disorder.

Inhaltsangabe

* Preface
* Contributors
* Chapter 1: Brain Imaging Techniques and their Application to Bipolar
Disorder, Caleb M. Adler
* Chapter 2: Structural Brain Abnormalities in Bipolar Disorder,
Marcella Bellani, Niccolò Zovetti, Marsal Sanches, Koji Matsuo, Jair
C. Soares, and Paolo Brambilla
* Chapter 3: Functional Brain Imaging in Bipolar Disorder: Activation
Studies, Dylan E. Kirsch, Valeria Tretyak, Stephen M. Strakowski, and
Elizabeth T.C. Lippard
* Chapter 4: Functional Brain Imaging in Bipolar Disorder: Connectivity
And Networks, Jennifer E. Siegel- Ramsay and Jorge R.C. Almeida
* Chapter 5: Neurochemical and Metabolic Imaging in Bipolar Disorder,
Muharrem Burak Baytunca, In Kyoon Lyoo, and Perry F. Renshaw
* Chapter 6: Cerebral Blood Flow in Bipolar Disorder: Past Findings and
Future Directions, Megan Mio, Mikaela K. Dimick, Simina Toma, Bradley
J. MacIntosh, and Benjamin I. Goldstein
* Chapter 7: Neuroimaging Studies of Bipolar Disorder in Youth,
Manpreet K. Singh and Melissa P. DelBello
* Chapter 8: Neuroimaging Differences Between Bipolar and Unipolar
Depression, Michele A. Bertocci, Jennifer E. Siegel- Ramsay, Jorge
R.C. Almeida, Stephen M. Strakowski, and Mary L. Phillips
* Chapter 9: Neuroimaging in Bipolar Disorder and Schizophrenia, Grace
Du and Dost Öngür
* Chapter 10: Genetic Techniques and Applications to Bipolar Disorder,
Yuhua Zhang, Melvin G. McInnis, and Sebastian Zöllner
* Chapter 11: General Genetics of Bipolar Disorder, John I. Nurnberger
Jr.
* Chapter 12: MiRNAs as Predictors of Bipolar Disorder Diagnosis and
Treatment Response, Yogesh Dwivedi
* Chapter 13: Genetics of Bipolar Disorder and Schizophrenia, Tim B.
Bigdeli and Philip D. Harvey
* Chapter 14: Mitochondrial Genetics and Bipolar Disorder, Christine
Konradi and Tadafumi Kato
* Chapter 15: Integration and Consolidation: A Neurophysiological Model
of Bipolar Disorder, Stephen M. Strakowski and Gin S. Malhi
* Index