The COST Manual of Laboratory Animal Care and Use (eBook, PDF)

Refinement, Reduction, and Research
Redaktion: Howard, Bryan; Perretta, Gemma; Nevalainen, Timo

• Format: PDF

Produktbeschreibung

COST (European Cooperation in the field of Scientific and Technical Research) is an intergovernmental initiative in science and research intended to promote the coordination of nationally funded research in Europe. Four working groups discuss the housing of animals, their environmental needs, refinement of procedures, genetically modified animals, and cost-benefit analysis. Based on the activities of these working groups, this book provides the European best practices for individuals and institutions working with laboratory animals. The text also discusses the ethical evaluation of experiments and procedures involving animals.

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Produktdetails

• Verlag: Taylor & Francis
• Seitenzahl: 439
• Erscheinungstermin: 19. April 2016
• Englisch
• ISBN-13: 9781439824931
• Artikelnr.: 56961868

Autorenporträt

Bryan Robert Howard is the former Director of Animal Welfare at the University of Sheffield. Timo Nevalainen is a Professor of the National Laboratory Animal Center at the University of Kuopio. Gemma Perretta is the Head of the Division of Special Zoology and Animal Models for the Institute of Neurobiology and Molecular Medicine of the Italian National Research Council in Rome.

Inhaltsangabe

Introduction. Design and Oversight of Laboratory Animal Facilities. Housing
and Care of Laboratory Animals. Animal Needs and Environmental Refinement.
Ethical Evaluation of Scientific Procedures: Recommendations for Ethics
Committees. Reduction by Careful Design and Statistical Analysis. Animal
Models: Selecting and Preparing Animals for a Study. Creation of
Genetically Modified Animals. Management of Genetically Modified Rodents.
Impact of Handling, Radiotelemetry, and Food Restriction. Basic Procedures:
Dosing, Sampling and Immunisation. Imaging Techniques. Anaesthesia and
Analgesia. Use of Humane Endpoints to Minimise Suffering. Euthanasia.
Education, Training and Competence. Animal Experimentation and Open
Communication.