Project Report from the year 2023 in the subject Biology - Micro- and Molecular Biology, grade: 4.27, University Of Abuja (FACULTY OF SCIENCE), course: MICROBIOLOGY, language: English, abstract: This study is on the efficacy of herbal mixtures on some selected bacteria, Staphylococcus aureus and Streptococcus pyogene was conducted. The zone diameter of inhibition in millimeter of Aqueous extracts of herbal mixture at concentration of 500 mg/ml against Staphylococcus aureus shows that Herbal mixture met the standard of the antibiotic used as the positive control (Chloramphenicol) with 25.0±1.0 mm each. Meanwhile Streptococcus pyogene had significant zone diameter of inhibition (24mm against the herbal mixtures) at concentration of 500mg/ml. The extracts of the herbal mixture had the minimum inhibition concentration (MIC) of 200 mg/ml against Staphylococcus aureus and which correlate with the control (Chloramphenicol), while the MIC of 400 mg/ml against Streptococcus pyogene respectively. The Minimum bactericidal concentration of the extracts shows that the herbal mixtures have the least value of 400 mg/ml which correlates with the standard antibiotic (Chloramphenicol) used as control against Streptococcus pyogene. The Herbal mixture had MBC of 400 mg/ml which also correlates with the standard antibiotics drug (Chloramphenicol).