This brilliant work describes the application of protein modification to proteomic research, covering sample preparation, sample prefractionation, analytical technologies, and validation issues in depth. Written by a recognized expert, it merges current proteomics concepts into established solution protein chemistry concepts. The author gives particular emphasis to the process by which a biomarker can be identified, validated, and developed into a diagnostic analyte that is useful in clinical applications. According to Proteomics, Lundblad resurrects the rigorous chemistry literature of the 1950's and 60's, on which most of our present-day knowledge is based.
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