The Genetics of Male Infertility (eBook, PDF)

Redaktion: Carrell, Douglas T.

• Format: PDF

Produktbeschreibung

In this book, twenty-one researchers and clinicians review the study of the genetics of male infertility, the tools available in the laboratory and clinic, the current state of knowledge, and the future of research and translation into clinical diagnostics and treatments.

New tools discussed are discussed. This book therefore serves as a guide to evidence-based clinical applications, and a preview of future possibilities.

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Produktdetails

• Verlag: Humana Press
• Seitenzahl: 337
• Erscheinungstermin: 8. November 2007
• Englisch
• ISBN-13: 9781597451765
• Artikelnr.: 37347530

Autorenporträt

Douglas T. Carrell, University of Utah School of Medicine, Salt Lake City, UT, USA

Inhaltsangabe

Methods and Tools for the Study.- The Genetics of Male Infertility in the Era of Genomics.- The Use of cDNA Libraries to Demonstrate a Linkage Between Transcription and Translation in Male Germ Cells.- Considerations When Using Array Technologies for Male Factor Assessment.- Microarray Analysis of a Large Number of Single-Nucleotide Polymorphisms in Individual Human Spermatozoa.- Physiological and Proteomic Approaches to Understanding Human Sperm Function.- Genetics of Idiopathic Male Infertility.- Meiosis and Errors of Meiosis.- The Immunocytogenetics of Human Male Meiosis.- The Clinical Relevance of Sperm Aneuploidy.- DNA Repair Genes and Genomic Instability in Severe Male Factor Infertility.- The Y Chromosome, Development Spermatogenesis, and Sperm Maturation.- Germ Cell-Specific Genes and Posttranscriptional Regulation in the Testis.- The Genetics of Cryptorchidism.- The Chromatoid Body and microRNA Pathways in Male Germ Cells.- Sperm Maturation in the Epididymis.- Clinical Applications of the Study of the Genetics of Male Infertility.- The Structure of the Y Chromosome and Its Role in Male Infertility.- Y Chromosome Microdeletions and Haplotypes.- The Genetics of Male Infertility.- The Future of the Diagnosis of Male (In) Fertility.- Polymorphisms and Male Infertility.- The Genetics of Abnormal Protamine Expression.- Chromatin Damage and Male Infertility.- Clinical Evaluation of the Genetics of Male Infertility.