The Human Hypothalamus (eBook, ePUB)

Neuroendocrine Disorders
Redaktion: Swaab, Dick F.; Kreier, Felix; Salehi, Ahmad; Lucassen, Paul J.; Buijs, Ruud M.

• Format: ePub

Produktbeschreibung

The Human Hypothalamus: Neuroendocrine Disorders, Volume 181 in the Handbook of Clinical Neurology series, provides comprehensive summaries of recent research on the brain and nervous system as they relate to clinical neurology. This volume summarizes the role of the hypothalamus in neuroendocrine disorders, identifying the mechanism of action, disorder etiology, and best practices for assessment and treatment. Disorders covered include pituitary hypothalamic disorders of development and growth, hypothalamic tumor related disorders, hypothalamic autoimmune disorders and infection, disorders of vasopressin, water and sodium homeostasis, eating disorders, and gonadotropic hormone regulation disorders.

• Discusses the importance of the hypothalamus in human growth and development
• Reviews hypothalamic related tumors, as well as pituitary, autoimmune, vasopressin and hormone regulation disorders
• Includes metabolic and eating disorders
• Identifies mechanisms of disease action and etiology
• Provides best practice information for assessment and treatment

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Produktdetails

• Verlag: Elsevier Science & Techn.
• Seitenzahl: 566
• Erscheinungstermin: 4. Juli 2021
• Englisch
• ISBN-13: 9780128206843
• Artikelnr.: 62245640

Inhaltsangabe

1. Introduction: The human hypothalamus and neuroendocrine disorders
SECTION 15  Structural disorders of the hypothalamo-pituitary region 2.
Pituitary stalk interruption syndrome  3. Empty sella syndrome: Multiple
endocrine disorders  4. Pituitary dysfunction after aneurysmal
subarachnoidal hemorrhage 5. Septo-optic dysplasia  SECTION 16  Tumors of
the hypothalamus 6. Hypothalamic hormone-producing tumors  7.
Craniopharyngiomas primarily affecting the hypothalamus  SECTION 17 
Neuroimmunological disorders 8. The stress-axis in multiple sclerosis:
Clinical, cellular, and molecular aspects  9. Neuroendocrine manifestations
of Langerhans cell histiocytosis  10. Neuroendocrine manifestations of
Erdheim-Chester disease 11. Hypothalamitis and pituitary atrophy  12.
Narcolepsy Type I as an autoimmune disorder  13. Neuromyelitis optica,
aquaporin-4 antibodies, and neuroendocrine disorders 14. Antibodies against
the pituitary and hypothalamus in boxers 15. Autoimmune diabetes insipidus 
SECTION 18  Drinking disorders 16. Neuroimaging of central diabetes
insipidus  17. Differential diagnosis of familial diabetes insipidus 18.
The vasopressin-aquaporin-2 pathway syndromes  19. Adipsic diabetes
insipidus  20. Animal models for diabetes insipidus  21. Nocturnal enuresis
in children: The role of arginine-vasopressin SECTION 19  Eating disorders
22. Monogenic human obesity syndromes 23. Hypothalamic microinflammation 
24. Glucose and fat sensing in the human hypothalamus  25. Hypothalamus and
neuroendocrine diseases: The use of human-induced pluripotent stem cells
for disease modeling  26. Prader-Willi syndrome: Hormone therapies 27.
Transcriptomics of the Prader-Willi syndrome hypothalamus  28. Disorders of
hypothalamic function: Insights from Prader-Willi syndrome and the effects
of craniopharyngioma  29. Animal models for Prader-Willi syndrome  30. Is
there a hypothalamic basis for anorexia nervosa?  SECTION 20  
Reproduction, olfaction and sexual behavior 31. Sexual differentiation of
the human hypothalamus: Relationship to gender identity and sexual
orientation 32. Klinefelter syndrome or testicular dysgenesis: Genetics,
endocrinology, and neuropsychology 33. Neurobiology of puberty and its
disorders