Anning Lin

The JNK Signaling Pathway (eBook, ePUB)

• Format: ePub

Produktbeschreibung

Signal transduction is one of the most exciting research areas in modern biology as it deals with how information flows from the extracellular environment into a living cell to change its metabolism, genotype and phenotype. With the completion of the genomes of human and several other species, it becomes even more important to elucidate the molecul

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Produktdetails

• Verlag: Taylor & Francis
• Erscheinungstermin: 15. Februar 2006
• Englisch
• ISBN-13: 9781040195079
• Artikelnr.: 72301172

Autorenporträt

Anning Lin Ph.D. is an Associate Professor at Ben M ay Institute for Cancer
Research and the Program Leader of the Cell Signaling and Gene Regulation
Program of Cancer Research Center, University of Chicago, U.S.A. His main
research interests include the function of the intracellular signaling network in
programmed cell death and tumorigenesis, using the c-Jun N-terminal protein
kinase (JNK) and IkB kinase (IKK) signaling pathways as molecular probes.

Inhaltsangabe

Preface 1. The Discovery of JNK and Its Biological Functions 2. Regulation
of JNK by Small GTPases 3. Physiological Roles of the Different JNKs:
Lessons from the JNK Knockouts 4. The Biological Function of JNKKs
(MKK4/MKK7 Knockout Mice) 5. The JNK Signal Transduction Pathway in
Drosophila 6. Regulation of Apoptosis by the JNK Signaling Pathway 7.
Oxidative Stress, JNK Activation and Cell Death 8. JNK as a Therapeutic
Target